Plasmin/antiplasmin Complex Products
(Plasmin/antiplasmin Complex)
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This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
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Recommended Plasmin/antiplasmin Complex Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, WB, ICC, IP
Validations
Cat. No.
ABIN7437467
Quantity
100 μL
Datasheet
Datasheet
Recommended Plasmin/antiplasmin Complex ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958599
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969342
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969341
Quantity
96 tests
Datasheet
Datasheet
Recommended Plasmin/antiplasmin Complex Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7424608
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Plasmin/antiplasmin Complex products
: "Plasminogen activator inhibitor-1 regulates macrophage-dependent postoperative adhesion by enhancing EGF-HER1 signaling in mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, Issue 6, pp. 2625-2637, (2017) (PubMed).: "The role of plasmin in the pathogenesis of murine multiple myeloma." in: Biochemical and biophysical research communications, Vol. 488, Issue 2, pp. 387-392, (2017) (PubMed).
: "Effect of ascorbate on fibrinolytic factors in septic mouse skeletal muscle." in: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, Vol. 25, Issue 7, pp. 745-53, (2015) (PubMed).
: "Long-term estrogen treatment of mice with a prothrombotic phenotype induces sustained increases in thrombin generation without affecting tissue fibrin deposition." in: Journal of thrombosis and haemostasis : JTH, Vol. 10, Issue 11, pp. 2392-4, (2014) (PubMed).
: "Massive amounts of tissue factor induce fibrinogenolysis without tissue hypoperfusion in rats." in: Shock (Augusta, Ga.), Vol. 39, Issue 6, pp. 514-9, (2013) (PubMed).
: "Markers of thrombogenesis and fibrinolysis and their relation to inflammation and endothelial activation in patients with idiopathic pulmonary arterial hypertension." in: PLoS ONE, Vol. 8, Issue 12, pp. e82628, (2013) (PubMed).
Synonyms and alternative names related to Plasmin/antiplasmin Complex
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (ASAP2), acid phosphatase, prostate (Acpp), 5'-NT, A030005E02Rik, Acpp11, AMAP2, CENTB3, DDEF2, FRAP, Lap, PAG3, PAP, pap, Pap-alpha, Ppal, RNACPP11, SHAG1Protein level used designations for Plasmin/antiplasmin Complex
- PYK2 C terminus-associated protein
- arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2
- centaurin, beta 3
- development and differentiation enhancing factor 2
- development and differentiation-enhancing factor 2
- paxillin-associated protein with ARF GAP activity 3
- pyk2 C-terminus-associated protein
- 5'-nucleotidase
- TMPase
- ecto-5'-nucleotidase
- fluoride-resistant acid phosphatase
- lysosomal acid phosphatase
- prostatic acid phosphatase
- thiamine monophosphatase
- prostatic acid phosphatase (rPAP)
Did you look for something else?
- Plasmin
- Plasmepsin-1
- PLAP
- Plakophilin 4
- Plakophilin 3
- Plakophilin 2
- Plakophilin 1
- PLAGL2
- PLAGL1
- PLAG1
- Placental Protein
- PLAC9
- PLAC8-Like 1
- PLAC8
- PLAC4
- PLAC2
- PLAC2
- PLAC1L
- PLAC1
- PLAA
- Plasminogen Activator
- Plasmodium Falciparum
- Plasmodium Falciparum Histidine Rich Protein 2
- Plasmodium Vivax MSP1
- Plasmolipin
- Plastin 3
- PLAT
- Platelet activating factor
- Platelet Factor 3
- Platelet Factor 4
- Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa)
- Platelet-Derived Growth Factor CC
- PLAU
- PLAUR
- PLBD1
- PLBD2
- PLBL1
- PLC
- PLC beta
- PLCB3
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