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Plakophilin 2 Products

(Plakophilin 2 (PKP2))

Categories

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008].

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Featured Plakophilin 2 Categories

Plakophilin 2 Antibodies

High quality antibodies with extensive validation data.

Plakophilin 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended Plakophilin 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC (p), ICC, IHC (fro), IF (p), IF (cc)
Validations
  • (1)
  • (2)
  • (1)
Cat. No. ABIN1386389
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
  • (1)
Cat. No. ABIN2786784
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7185427
Quantity 100 μg
Datasheet Datasheet

Recommended Plakophilin 2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN512304
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN512337
Quantity 96 tests
Datasheet Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN777427
Quantity 96 tests
Datasheet Datasheet

Recommended Plakophilin 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1315254
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415632
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3086065
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Plakophilin 2 products

van Opbergen, Noorman, Pfenniger, Copier, Vermij, Li, van der Nagel, Zhang, de Bakker, Glass, Mohler, Taffet, Vos, van Rijen, Delmar, van Veen: "Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress." in: International journal of molecular sciences, Vol. 20, Issue 17, (2020) (PubMed).

Wang, Fu, Li, Patil, Liu, Dorf, Li: "Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction." in: Nature communications, Vol. 8, pp. 13876, (2018) (PubMed).

Akdis, Medeiros-Domingo, Gaertner-Rommel, Kast, Enseleit, Bode, Klingel, Kandolf, Renois, Andreoletti, Akdis, Milting, Lüscher, Brunckhorst, Saguner, Duru: "Myocardial expression profiles of candidate molecules in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia compared to those with dilated cardiomyopathy and healthy controls." in: Heart rhythm, Vol. 13, Issue 3, pp. 731-41, (2016) (PubMed).

Sobolik-Delmaire, Reddy, Pashaj, Roberts, Wahl: "Plakophilin-1 localizes to the nucleus and interacts with single-stranded DNA." in: The Journal of investigative dermatology, Vol. 130, Issue 11, pp. 2638-46, (2010) (PubMed).

Christensen, Benn, Tybjaerg-Hansen, Haunso, Svendsen: "Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients--disease-causing or innocent bystanders?" in: Cardiology, Vol. 115, Issue 2, pp. 148-54, (2010) (PubMed).

Mertens, Kuhn, Franke: "Plakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque." in: The Journal of cell biology, Vol. 135, Issue 4, pp. 1009-25, (1997) (PubMed).

Synonyms and alternative names related to Plakophilin 2

plakophilin 2 (PKP2), plakophilin 2 (Pkp2), 1200008D14Rik, 1200012P04Rik, AA516617, ARVD9, Pkp2l

Protein level used designations for Plakophilin 2

  • plakophilin-2
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