PLA2G4A Products
(Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
Categories
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008].
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Featured PLA2G4A Categories
PLA2G4A Antibodies
High quality antibodies with extensive validation data.
PLA2G4A ELISA Kits
Reliable ELISA kits for a wide range of species.
PLA2G4A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PLA2G4A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7438268
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN3187717
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7437737
Quantity
100 μL
Datasheet
Datasheet
Recommended PLA2G4A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958564
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969300
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969299
Quantity
96 tests
Datasheet
Datasheet
Recommended PLA2G4A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315289
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7394447
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7394444
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PLA2G4A products
: "The synergistic mechanism of total saponins and flavonoids in Notoginseng-Safflower pair against myocardial ischemia uncovered by an integrated metabolomics strategy." in: Biomedicine & pharmacotherapy, Vol. 130, pp. 110574, (2020) (PubMed).: "Reduced group IVA phospholipase A2 expression is associated with unfavorable outcome for patients with gastric cancer." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 1, pp. 454, (2013) (PubMed).
: "The innate immune response to coxsackievirus B3 predicts progression to cardiovascular disease and heart failure in male mice." in: Biology of sex differences, Vol. 2, pp. 2, (2011) (PubMed).
: "JNK and ceramide kinase govern the biogenesis of lipid droplets through activation of group IVA phospholipase A2." in: The Journal of biological chemistry, Vol. 284, Issue 47, pp. 32359-69, (2009) (PubMed).
Synonyms and alternative names related to PLA2G4A
phospholipase A2 group IVA (PLA2G4A), phospholipase A2 group IVA (Pla2g4a), phospholipase A2 group IVA L homeolog (pla2g4a.L), phospholipase A2, group IVA (cytosolic, calcium-dependent) (Pla2g4a), phospholipase A2, group IVAb (cytosolic, calcium-dependent) (pla2g4ab), cPLA2, CPLA2, cPLA2-alpha, cPLA2alpha, PLA2, Pla2c, PLA2G1B, PLA2G4, Pla2g4, pla2g4, PLA2G4A, pla2g4a, si:dkey-97o5.1Protein level used designations for PLA2G4A
- cPLA2
- calcium-dependent phospholipid-binding protein
- cytosolic phospholipase A2
- lysophospholipase
- phosphatidylcholine 2-acylhydrolase
- phospholipase A2 group IVA
- phospholipase A2 cytosolic
- Phospholipase A2 group IVA
- phospholipase A2, group IB (pancreas)
- Cytosolic phospholipase A2 (CPLA2)
- Type IV PLA2
- cPLA2-alpha
- cytosolic PLA2
- phospholipase A2, group 4
- phospholipase A2, group IVA (cytosolic, calcium-dependent)
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