PKN1 Products
(Protein Kinase N1 (PKN1))
Categories
The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
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Featured PKN1 Categories
PKN1 Antibodies
High quality antibodies with extensive validation data.
PKN1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PKN1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PKN1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, ICC, FACS
Validations
- (6)
Cat. No.
ABIN5542353
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IP, RNAi
Validations
- (6)
Cat. No.
ABIN562393
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (5)
Cat. No.
ABIN1682293
Quantity
100 μg
Datasheet
Datasheet
Recommended PKN1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958932
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1116807
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1116808
Quantity
96 tests
Datasheet
Datasheet
Recommended PKN1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315236
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315234
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509112
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PKN1 products
: "Detecting protein-phospholipid interactions. Epidermal growth factor-induced activation of phospholipase D1b in situ." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22974-9, (2002) (PubMed).: "Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase." in: The Journal of biological chemistry, Vol. 275, Issue 15, pp. 11064-70, (2000) (PubMed).
: "Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family." in: European journal of biochemistry / FEBS, Vol. 227, Issue 1-2, pp. 344-51, (1995) (PubMed).
: "Activation of PKN, a novel 120-kDa protein kinase with leucine zipper-like sequences, by unsaturated fatty acids and by limited proteolysis." in: Biochemical and biophysical research communications, Vol. 204, Issue 1, pp. 348-56, (1994) (PubMed).
Synonyms and alternative names related to PKN1
protein kinase N1 (PKN1), protein kinase N1 (Pkn1), protein kinase N1b (pkn1b), protein kinase N1 (pkn1), Protein kinase N (Pkn), 3-2, CG2049, CG2055, CT6637, CT6660, DBK, Dmel\\CG2049, DPKN, Dpkn, dPKN, F730027O18Rik, l(2)06736, l(2)45Ca, PAK-1, PAK1, Pk45C, Pk?3, PKN, Pkn, PKN-ALPHA, PKN1, PRK1, PRK2, PRKCL1, Prkcl1, Stk3, v(2)rG232Protein level used designations for PKN1
- protease-activated kinase 1
- protein kinase C-like 1
- protein kinase C-like PKN
- protein kinase C-related kinase 1
- protein kinase PKN-alpha
- protein-kinase C-related kinase 1
- serine-threonine kinase N
- serine-threonine protein kinase N
- serine/threonine protein kinase N
- serine/threonine-protein kinase N1
- serine/threonine kinase 3
- protein kinase N1
- serine/threonine-protein kinase N1-like
- protein kinase PKN
- CG2049-PB
- CG2049-PC
- CG2049-PD
- CG2049-PE
- CG2049-PF
- CG2049-PG
- CG2049-PH
- CG2049-PI
- CG2049-PJ
- CG2049-PK
- CG2049-PL
- CG2049-PM
- Pkn-PB
- Pkn-PC
- Pkn-PD
- Pkn-PE
- Pkn-PF
- Pkn-PG
- Pkn-PH
- Pkn-PI
- Pkn-PJ
- Pkn-PK
- Pkn-PL
- Pkn-PM
- protein kinase N
- protein kinase c related
- protein kinase related to protein kinase N
- protein kinase-like 45C
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