PKLR Products
(Pyruvate Kinase, Liver and RBC (PKLR))
Categories
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured PKLR Categories
PKLR Antibodies
High quality antibodies with extensive validation data.
PKLR ELISA Kits
Reliable ELISA kits for a wide range of species.
PKLR Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PKLR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7431302
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7431305
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (4)
Cat. No.
ABIN950030
Quantity
100 μL
Datasheet
Datasheet
Recommended PKLR ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6959012
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959013
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959014
Quantity
96 tests
Datasheet
Datasheet
Recommended PKLR Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7275451
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315223
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315225
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PKLR products
: "Time-Dependent Changes in the Serum Levels of Neurobiochemical Factors After Acute Methadone Overdose in Adolescent Male Rat." in: Cellular and molecular neurobiology, (2020) (PubMed).: "Contact system activation and high thrombin generation in hyperthyroidism." in: European journal of endocrinology, Vol. 176, Issue 5, pp. 583-589, (2017) (PubMed).
: "The effects of PGC-1α on the proliferation and energy metabolism of malignant endometrial cancer cells." in: OncoTargets and therapy, Vol. 8, pp. 769-74, (2015) (PubMed).
: "Association of C-terminal region of phosphoglycerate mutase with glycolytic complex regulates energy production in cancer cells." in: Journal of cellular physiology, Vol. 227, Issue 6, pp. 2613-21, (2012) (PubMed).
: "Proteomic analyses of transgenic LQT1 and LQT2 rabbit hearts elucidate an increase in expression and activity of energy producing enzymes." in: Journal of proteomics, Vol. 75, Issue 17, pp. 5254-65, (2012) (PubMed).
: "The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells." in: Molecular biology of the cell, Vol. 21, Issue 19, pp. 3449-58, (2010) (PubMed).
: "Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians." in: Diabetes, Vol. 51, Issue 9, pp. 2861-5, (2002) (PubMed).
: "Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia." in: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23807-14, (2002) (PubMed).
: "PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations." in: Human genetics, Vol. 110, Issue 6, pp. 532-44, (2002) (PubMed).
Synonyms and alternative names related to PKLR
pyruvate kinase L/R (PKLR), pyruvate kinase, liver and RBC (Pklr), pyruvate kinase L/R (pklr), pyruvate kinase, liver and RBC L homeolog (pklr.L), pyruvate kinase, liver and RBC (pklr), pyruvate kinase, liver and RBC (PKLR), pyruvate kinase liver and red blood cell (Pklr), pyruvate kinase L/R (Pklr), pyruvate kinase PKLR-like (LOC100621940), Pk-1, PK1, pk1, Pk1, PKL, Pklg, PKLR, pklr, PKR, PKRL, R-PK, RPK, wu:fd15e01, wu:fi37e08Protein level used designations for PKLR
- R-type/L-type pyruvate kinase
- pyruvate kinase 1
- pyruvate kinase PKLR
- pyruvate kinase isozyme R/L
- pyruvate kinase isozymes L/R
- pyruvate kinase isozymes R/L
- pyruvate kinase type L
- pyruvate kinase, liver and blood cell
- red cell/liver pyruvate kinase
- L-PK
- pyruvate kinase, liver and red blood cell
- pyruvate kinase, liver and RBC
- Pyruvate kinase isozyme R
- Pyruvate kinase isozymes R/L
- pyruvate kinase isozymes R/L-like
- secretory carrier-associated membrane protein 3-like
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