PKD2 Products
(Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
Categories
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011].
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Featured PKD2 Categories
PKD2 Antibodies
High quality antibodies with extensive validation data.
PKD2 ELISA Kits
Reliable ELISA kits for a wide range of species.
PKD2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PKD2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (4)
Cat. No.
ABIN562252
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7163836
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN3182238
Quantity
100 μL
Datasheet
Datasheet
Recommended PKD2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969449
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380357
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN5595162
Quantity
96 tests
Datasheet
Datasheet
Recommended PKD2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315202
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509111
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3131487
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PKD2 products
: "Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation." in: Journal of the American Society of Nephrology : JASN, Vol. 27, Issue 9, pp. 2645-57, (2016) (PubMed).: "Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer. ..." in: International journal of cancer. Journal international du cancer, Vol. 136, Issue 7, pp. 1515-27, (2015) (PubMed).
: "Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity." in: Scientific reports, Vol. 5, pp. 13461, (2015) (PubMed).
: "Genotype-phenotype correlation in children with autosomal dominant polycystic kidney disease." in: Pediatric nephrology (Berlin, Germany), Vol. 24, Issue 5, pp. 983-9, (2009) (PubMed).
: "Polycystin channels and kidney disease." in: Trends in pharmacological sciences, Vol. 22, Issue 11, pp. 543-6, (2001) (PubMed).
: "Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations." in: Nature genetics, Vol. 25, Issue 2, pp. 143-4, (2000) (PubMed).
: "In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2." in: The Journal of biological chemistry, Vol. 275, Issue 42, pp. 32888-93, (2000) (PubMed).
Synonyms and alternative names related to PKD2
polycystin 2, transient receptor potential cation channel (PKD2), polycystic kidney disease 2 (Pkd2), polycystin 2, transient receptor potential cation channel (Pkd2), Polycystin-2 (pkd-2), polycystin 2, transient receptor potential cation channel L homeolog (pkd2.L), polycystic kidney disease 2 (pkd2), APKD2, C030034P18Rik, Cup, Pc-2, PC2, pkd2, PKD2L1, PKD4, RGD1559992, TRPP2, trpp2Protein level used designations for PKD2
- R48321
- autosomal dominant polycystic kidney disease type II protein
- polycystin-2
- polycystwin
- transient receptor potential cation channel, subfamily P, member 2
- polycystic kidney disease 2 protein homolog
- polycystin 2
- polycystic kidney disease 2 homolog
- polycystic kidney disease 2 membrane protein
- cation channel
- polycystic kidney disease 2 (autosomal dominant) L homeolog
- polycystin-2-like
- Curly up
- Polycystic kidney disease 2 protein homolog
- TRPP2
- Transient receptor potential cation channel subfamily P member 2
- cup
- curly up
- transient receptor potential cation channel subfamily P member 2
- polycystic kidney disease 2 (autosomal dominant)
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