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PKD1 Proteins

(Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene. Also, six pseudogenes, closely linked in a known duplicated region on chromosome 16p, have been described. [provided by RefSeq, Oct 2008].

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PKD1 Protein (AA 177-359) (His tag) (ABIN7505263)

PKD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

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PKD1 Proteins by Origin

Find PKD1 Proteins for a variety of species such as anti-Human PKD1. The species listed below are among those available. Click on a link to go to the corresponding products.

PKD1 Proteins by Source

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PKD1 Proteins by Protein Type

Here you can find PKD1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Popular PKD1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

PKD1 Protein (AA 177-359) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7505263

Quantity 100 μg

Datasheet Datasheet

Aliases for PKD1 Proteins

polycystin 1, transient receptor potential channel interacting (PKD1) Proteins
polycystin 1, transient receptor poteintial channel interacting (Pkd1) Proteins
polycystin 1, transient receptor potential channel interacting (Pkd1) Proteins
polycystin-1 (LOC749291) Proteins
mFLJ00285 Proteins
PBP Proteins
Pc-1 Proteins
PC1 Proteins
TRPP1 Proteins

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