PKC theta Products
(Protein Kinase C, theta (PRKCQ))
Categories
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008].
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Featured PKC theta Categories
PKC theta Antibodies
High quality antibodies with extensive validation data.
PKC theta ELISA Kits
Reliable ELISA kits for a wide range of species.
PKC theta Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PKC theta Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (5)
Cat. No.
ABIN6256401
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7443020
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1501904
Quantity
100 μL
Datasheet
Datasheet
Recommended PKC theta ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962224
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1116786
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1116787
Quantity
96 tests
Datasheet
Datasheet
Recommended PKC theta Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316274
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509109
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7415938
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PKC theta products
: "Evidence of microglial activation following exposure to serum from first-onset drug-naïve schizophrenia patients." in: Brain, behavior, and immunity, Vol. 67, pp. 364-373, (2018) (PubMed).: "Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation." in: BMC cell biology, Vol. 14, pp. 39, (2013) (PubMed).
: "Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells." in: The FEBS journal, Vol. 273, Issue 8, pp. 1843-54, (2006) (PubMed).
: "Catalytic domain crystal structure of protein kinase C-theta (PKCtheta)." in: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 50401-9, (2004) (PubMed).
: "Characterization of TCR-induced phosphorylation of PKCtheta in primary murine lymphocytes." in: Molecular immunology, Vol. 40, Issue 13, pp. 931-42, (2004) (PubMed).
: "Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in ..." in: Blood, Vol. 103, Issue 3, pp. 948-54, (2004) (PubMed).
: "Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta." in: The Journal of biological chemistry, Vol. 279, Issue 18, pp. 18623-32, (2004) (PubMed).
: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).
: "Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes." in: Molecular biology of the cell, Vol. 15, Issue 6, pp. 2932-42, (2004) (PubMed).
: "Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28315-9, (2004) (PubMed).
Synonyms and alternative names related to PKC theta
protein kinase C theta (PRKCQ), protein kinase C eta (PRKCH), protein kinase C, theta (Prkcq), protein kinase C theta (Prkcq), A130035A12Rik, AW494342, nPKC-theta, PKC-0, PKC-theta, Pkcq, PKCtheta, PRKCTProtein level used designations for PKC theta
- protein kinase C theta type
- PKC theta
- nPKC-theta
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