PKC alpha Products
(Protein Kinase C, alpha (PKCa))
Categories
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008].
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Featured PKC alpha Categories
PKC alpha Antibodies
High quality antibodies with extensive validation data.
PKC alpha ELISA Kits
Reliable ELISA kits for a wide range of species.
PKC alpha Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PKC alpha Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), PLA
Validations
- (6)
Cat. No.
ABIN562379
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN391001
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IP, FACS, IF, ICC
Validations
- (8)
Cat. No.
ABIN4904772
Quantity
100 μL
Datasheet
Datasheet
Recommended PKC alpha ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969711
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969712
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969713
Quantity
96 tests
Datasheet
Datasheet
Recommended PKC alpha Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316255
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Xenopus laevis
Source
Insect Cells
Validations
Cat. No.
ABIN5509223
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7412596
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PKC alpha products
: "Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 58, pp. 152893, (2019) (PubMed).: "Adenosine receptor expression in the adult zebrafish retina." in: Purinergic signalling, Vol. 15, Issue 3, pp. 327-342, (2019) (PubMed).
: "Olfactory Ensheathing Cells Inhibit Gliosis in Retinal Degeneration by Downregulation of the Müller Cell Notch Signaling Pathway." in: Cell transplantation, Vol. 26, Issue 6, pp. 967-982, (2018) (PubMed).
: "A group I metabotropic glutamate receptor controls synaptic gain between rods and rod bipolar cells in the mouse retina." in: Physiological reports, Vol. 6, Issue 20, pp. e13885, (2018) (PubMed).
: "Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells." in: Oncotarget, Vol. 8, Issue 51, pp. 88630-88644, (2017) (PubMed).
: "Fragile X Mental Retardation Protein expression in the retina is regulated by light." in: Experimental eye research, Vol. 146, pp. 72-82, (2016) (PubMed).
: "Molecular Mechanism of the Cell Death Induced by the Histone Deacetylase Pan Inhibitor LBH589 (Panobinostat) in Wilms Tumor Cells. ..." in: PLoS ONE, Vol. 10, Issue 7, pp. e0126566, (2016) (PubMed).
: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." in: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).
: "Suppression of A549 cell proliferation and metastasis by calycosin via inhibition of the PKC-α/ERK1/2 pathway: An in vitro investigation." in: Molecular medicine reports, Vol. 13, Issue 4, pp. 3709-10, (2016) (PubMed).
: "Syndecan-4 Promotes Epithelial Tumor Cells Spreading and Regulates the Turnover of PKC? Activity under Mechanical Stimulation on the Elastomeric Substrates." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 4, pp. 1291-1304, (2015) (PubMed).
Synonyms and alternative names related to PKC alpha
protein kinase C alpha (PRKCA), protein kinase C, alpha L homeolog (prkca.L), protein kinase C, alpha (prkca), protein kinase C, alpha (Prkca), protein kinase C alpha (Prkca), AAG6, AI875142, im:7139045, LOC100219195, pkc-alpha, PKC-alpha, PKCA, Pkca, pkcalpha, PKRCA, PRKACA, si:dkey-8l19.1Protein level used designations for PKC alpha
- pkc-like 2
- protein kinase C alpha type
- protein kinase C, alpha
- protein kinase C alpha type-like
- PKC-A
- aging-associated gene 6
- PKC-alpha
- protein kinase c-alpha
- protein kinase, C alpha
- protein kinase C alpha
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