PIP5K1C Products
(Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C))
Categories
This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010].
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Featured PIP5K1C Categories
PIP5K1C Antibodies
High quality antibodies with extensive validation data.
PIP5K1C Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PIP5K1C Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN392596
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7191891
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN392595
Quantity
400 μL
Datasheet
Datasheet
Recommended PIP5K1C Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315143
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315145
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509095
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PIP5K1C products
: "Comparative analysis of normal versus CLL B-lymphocytes reveals patient-specific variability in signaling mechanisms controlling LFA-1 activation by chemokines." in: Cancer research, Vol. 69, Issue 24, pp. 9281-90, (2009) (PubMed).: "Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module." in: Nature immunology, Vol. 10, Issue 2, pp. 185-94, (2009) (PubMed).
: "Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin." in: Nature, Vol. 420, Issue 6911, pp. 85-9, (2002) (PubMed).
: "Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions." in: Nature, Vol. 420, Issue 6911, pp. 89-93, (2002) (PubMed).
: "Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8741-8, (1998) (PubMed).
: "Association of protein kinase Cmu with type II phosphatidylinositol 4-kinase and type I phosphatidylinositol-4-phosphate 5-kinase." in: The Journal of biological chemistry, Vol. 273, Issue 36, pp. 23126-33, (1998) (PubMed).
: "Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate." in: The Journal of biological chemistry, Vol. 273, Issue 29, pp. 18040-6, (1998) (PubMed).
Synonyms and alternative names related to PIP5K1C
phosphatidylinositol-4-phosphate 5-kinase type 1 gamma (PIP5K1C), phosphatidylinositol-4-phosphate 5-kinase type 1 gamma (Pip5k1c), phosphatidylinositol-4-phosphate 5-kinase, type I, gamma S homeolog (pip5k1c.S), phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (PIP5K1C), phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (pip5k1c), phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma (Pip5k1c), AI115456, AI835305, LCCS3, MGC130766, PIP5K-GAMMA, PIP5K1C, PIP5Kgamma, Pip5kIgamma, PIPKIg_v4Protein level used designations for PIP5K1C
- Human homolog of mouse phosphatidylinositol-4-phosphate 5-kinase I-gamma
- PIP5K1-gamma
- diphosphoinositide kinase
- phosphatidylinositol 4-phosphate 5-kinase type I gamma
- phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
- phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
- ptdIns(4)P-5-kinase 1 gamma
- type I PIP kinase
- PIP5KIgamma
- phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
- ptdIns(4)P-5-kinase gamma
- ptdInsPKIgamma
- phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
- phosphatidylinositol-4-phosphate 5-kinase type I gamma
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