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PIP4K2A Products

(Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))

Categories

Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq, Jul 2008].

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Featured PIP4K2A Categories

PIP4K2A Antibodies

High quality antibodies with extensive validation data.

PIP4K2A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIP4K2A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN6243276
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN562246
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6145673
Quantity 100 μL
Datasheet Datasheet

Recommended PIP4K2A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6220517
Quantity 96 tests
Datasheet Datasheet

Recommended PIP4K2A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124405
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315125
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315123
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PIP4K2A products

Jones, Foulger, Keune, Bultsma, Divecha: "PtdIns5P is an oxidative stress-induced second messenger that regulates PKB activation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 4, pp. 1644-56, (2013) (PubMed).

Keune, Jones, Bultsma, Sommer, Zhou, Lu, Divecha: "Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress." in: Science signaling, Vol. 5, Issue 252, pp. ra86, (2012) (PubMed).

Huang, Anderson, Cao, Wiechmann, Rajala: "Light-induced tyrosine phosphorylation of rod outer segment membrane proteins regulate the translocation, membrane binding and activation of type II ? phosphatidylinositol-5-phosphate 4-kinase." in: Neurochemical research, Vol. 36, Issue 4, pp. 627-35, (2011) (PubMed).

Bultsma, Keune, Divecha: "PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4Kalpha." in: The Biochemical journal, Vol. 430, Issue 2, pp. 223-35, (2010) (PubMed).

Wilcox, Hinchliffe: "Regulation of extranuclear PtdIns5P production by phosphatidylinositol phosphate 4-kinase 2alpha." in: FEBS letters, Vol. 582, Issue 9, pp. 1391-4, (2008) (PubMed).

Rozenvayn, Flaumenhaft: "Protein kinase C mediates translocation of type II phosphatidylinositol 5-phosphate 4-kinase required for platelet alpha-granule secretion." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8126-34, (2003) (PubMed).

Synonyms and alternative names related to PIP4K2A

phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (Pip4k2a), phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (Pip4k2a), phosphatidylinositol-5-phosphate 4-kinase, type II, alpha S homeolog (pip4k2a.S), phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (pip4k2a), phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a (pip4k2aa), AW742916, PI5P4KA, pi5p4ka, pip4k2a, PIP5K2A, Pip5k2a, pip5k2a, PIP5KII-alpha, PIP5KIIA, pip5kiia, PIPK, pipk, zgc:194746, zgc:194777

Protein level used designations for PIP4K2A

  • 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha
  • 1-phosphatidylinositol-4-phosphate kinase
  • 1-phosphatidylinositol-4-phosphate-5-kinase
  • 1-phosphatidylinositol-5-phosphate 4-kinase 2-alpha
  • PI(5)P 4-kinase type II alpha
  • PIP4KII-alpha
  • PIP5KIII
  • PIP5KIIalpha
  • PtdIns(4)P-5-kinase B isoform
  • diphosphoinositide kinase 2-alpha
  • phosphatidylinositol 5-phosphate 4-kinase type II alpha
  • phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
  • phosphatidylinositol-4-phosphate 5-kinase, type II, alpha
  • phosphatidylinositol-5-phosphate 4-kinase type-2 alpha
  • ptdIns(4)P-5-kinase C isoform
  • ptdIns(5)P-4-kinase isoform 2-alpha
  • type II phosphatidylinositol-4-phosphate 5-kinase 53 K isoform
  • 1-phosphatidylinositol-5-phosphate 4-kinase A
  • PIPK2 alpha
  • phosphatidylinositol-4-phosphate 5-kinase type II alpha
  • pip5kii-alpha
  • phosphatidylinositol-4-phosphate-5-kinase
  • phosphatidylinositol-5-phosphate 4-kinase type II alpha
  • phosphatidylinositol-5-phosphate 4-kinase, type II, alpha, genome duplicate a
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