PILRA Products
(Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
Categories
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq, Jul 2008].
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Featured PILRA Categories
PILRA Antibodies
High quality antibodies with extensive validation data.
PILRA ELISA Kits
Reliable ELISA kits for a wide range of species.
PILRA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PILRA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (3)
Cat. No.
ABIN565452
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7162515
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6738289
Quantity
100 μL
Datasheet
Datasheet
Recommended PILRA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4884161
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730208
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6384782
Quantity
96 tests
Datasheet
Datasheet
Recommended PILRA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275476
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275475
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275474
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PILRA products
: "Differential effects on cell fusion activity of mutations in herpes simplex virus 1 glycoprotein B (gB) dependent on whether a gD receptor or a gB receptor is overexpressed." in: Journal of virology, Vol. 83, Issue 15, pp. 7384-90, (2009) (PubMed).Synonyms and alternative names related to PILRA
paired immunoglobin like type 2 receptor alpha (PILRA), paired immunoglobulin-like type 2 receptor alpha (LOC489841), paired immunoglobin-like type 2 receptor alpha (Pilra), AV021745, FDF03, PILRA, RGD1562847Protein level used designations for PILRA
- paired immunoglobulin-like type 2 receptor alpha
- paired immunoglobin-like type 2 receptor alpha
- cell surface receptor FDF03
- inhibitory receptor PILR-alpha
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