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PILRA Products

(Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq, Jul 2008].

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Featured PILRA Categories

PILRA Antibodies

High quality antibodies with extensive validation data.

PILRA ELISA Kits

Reliable ELISA kits for a wide range of species.

PILRA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PILRA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN565452
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7162515
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6738289
Quantity 100 μL
Datasheet Datasheet

Recommended PILRA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884161
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730208
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384782
Quantity 96 tests
Datasheet Datasheet

Recommended PILRA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275476
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275475
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275474
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PILRA products

Fan, Lin, Satoh, Arase, Spear: "Differential effects on cell fusion activity of mutations in herpes simplex virus 1 glycoprotein B (gB) dependent on whether a gD receptor or a gB receptor is overexpressed." in: Journal of virology, Vol. 83, Issue 15, pp. 7384-90, (2009) (PubMed).

Synonyms and alternative names related to PILRA

paired immunoglobin like type 2 receptor alpha (PILRA), paired immunoglobulin-like type 2 receptor alpha (LOC489841), paired immunoglobin-like type 2 receptor alpha (Pilra), AV021745, FDF03, PILRA, RGD1562847

Protein level used designations for PILRA

  • paired immunoglobulin-like type 2 receptor alpha
  • paired immunoglobin-like type 2 receptor alpha
  • cell surface receptor FDF03
  • inhibitory receptor PILR-alpha
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