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PIK3R4 Products

(Phosphoinositide 3-kinase Regulatory Subunit 4 (PIK3R4))

Categories

Regulatory subunit of the PI3K complex. May regulate membrane trafficking late in the endocytic pathway (By similarity).

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Featured PIK3R4 Categories

PIK3R4 Antibodies

High quality antibodies with extensive validation data.

PIK3R4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIK3R4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
  • (5)
Cat. No. ABIN565478
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, ICC, FACS
Validations
  • (5)
Cat. No. ABIN7193536
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (5)
Cat. No. ABIN565477
Quantity 100 μg
Datasheet Datasheet

Recommended PIK3R4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6212363
Quantity 96 tests
Datasheet Datasheet

Recommended PIK3R4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315088
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2728973
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our PIK3R4 products

Gstrein, Edwards, Přistoupilová, Leca, Breuss, Pilat-Carotta, Hansen, Tripathy, Traunbauer, Hochstoeger, Rosoklija, Repic, Landler, Stránecký, Dürnberger, Keane, Zuber, Adams, Flint, Honzik, Gut et al.: "Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. ..." in: Nature neuroscience, Vol. 21, Issue 2, pp. 207-217, (2018) (PubMed).

Liu, Hu, Luo, Yue, Wang, Chen, Zhou, Wang, Cai, Hu, Ke, Yang, Hu: "Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 37, Issue 11, pp. 2075-2086, (2017) (PubMed).

Stoetzel, Bär, De Craene, Scheidecker, Etard, Chicher, Reck, Perrault, Geoffroy, Chennen, Strähle, Hammann, Friant, Dollfus: "A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi." in: Nature communications, Vol. 7, pp. 13586, (2016) (PubMed).

Kaushik, Cuervo: "Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis." in: Nature cell biology, Vol. 17, Issue 6, pp. 759-70, (2015) (PubMed).

Hirsch, Shen, Dokmanovic, Yu, Mohan, Elzarrad, Wu: "Insulin activation of vacuolar protein sorting 34 mediates localized phosphatidylinositol 3-phosphate production at lamellipodia and activation of mTOR/S6K1." in: Cellular signalling, Vol. 26, Issue 6, pp. 1258-68, (2014) (PubMed).

Bejarano, Yuste, Patel, Stout, Spray, Cuervo: "Connexins modulate autophagosome biogenesis." in: Nature cell biology, Vol. 16, Issue 5, pp. 401-14, (2014) (PubMed).

Devereaux, DallArmi, Alcazar-Roman, Ogasawara, Zhou, Wang, Yamamoto, De Camilli, Di Paolo: "Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis." in: PLoS ONE, Vol. 8, Issue 10, pp. e76405, (2013) (PubMed).

Pampliega, Orhon, Patel, Sridhar, Díaz-Carretero, Beau, Codogno, Satir, Satir, Cuervo: "Functional interaction between autophagy and ciliogenesis." in: Nature, Vol. 502, Issue 7470, pp. 194-200, (2013) (PubMed).

Matsunaga, Morita, Saitoh, Akira, Ktistakis, Izumi, Noda, Yoshimori: "Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L." in: The Journal of cell biology, Vol. 190, Issue 4, pp. 511-21, (2010) (PubMed).

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Synonyms and alternative names related to PIK3R4

phosphoinositide-3-kinase, regulatory subunit 4 (pik3r4), phosphoinositide-3-kinase regulatory subunit 4 (PIK3R4), phosphoinositide-3-kinase regulatory subunit 4 (pik3r4), phosphoinositide-3-kinase regulatory subunit 4 (Pik3r4), phosphoinositide-3-kinase, regulatory subunit 4 (Pik3r4), 2210010O15Rik, C85833, C730038E05Rik, D9Ertd418e, im:7148788, p150, VPS15

Protein level used designations for PIK3R4

  • phosphoinositide-3-kinase, regulatory subunit 4
  • phosphoinositide 3-kinase regulatory subunit 4
  • PI3-kinase regulatory subunit 4
  • phosphoinositide 3-kinase regulatory subunit 4-like
  • PI3-kinase p150 subunit
  • phosphatidylinositol 3-kinase-associated p150
  • phosphoinositide 3-kinase adaptor protein
  • phosphoinositide-3-kinase, regulatory subunit 4, p150
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