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PIK3R3 Products

(Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))

Categories

Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.

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Featured PIK3R3 Categories

PIK3R3 Antibodies

High quality antibodies with extensive validation data.

PIK3R3 ELISA Kits

Reliable ELISA kits for a wide range of species.

PIK3R3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIK3R3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (4)
  • (3)
Cat. No. ABIN392576
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (4)
Cat. No. ABIN521950
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7163172
Quantity 100 μL
Datasheet Datasheet

Recommended PIK3R3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5690933
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1147778
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1147779
Quantity 96 tests
Datasheet Datasheet

Recommended PIK3R3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315084
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315086
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3085385
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PIK3R3 products

Yang, Cheng, Zhou, Zhu, Hu, Yang: "Overexpression of X-Box Binding Protein 1 (XBP1) Correlates to Poor Prognosis and Up-Regulation of PI3K/mTOR in Human Osteosarcoma." in: International journal of molecular sciences, Vol. 16, Issue 12, pp. 28635-46, (2016) (PubMed).

Munkley, Livermore, McClurg, Kalna, Knight, McCullagh, McGrath, Crundwell, Leung, Robson, Harries, Rajan, Elliott: "The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells." in: Oncoscience, Vol. 2, Issue 9, pp. 755-64, (2015) (PubMed).

Wang, Yang, Jin, Deng, Luo, Hu, Wang: "TGF-? regulates the proliferation of lung adenocarcinoma cells by inhibiting PIK3R3 expression." in: Molecular carcinogenesis, (2014) (PubMed).

Xu, Wen, Zhou, Liu, Li, Fei, Luo, Ren: "MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway." in: Molecular biology of the cell, Vol. 24, Issue 1, pp. 42-55, (2012) (PubMed).

Eiring, Neviani, Santhanam, Oaks, Chang, Notari, Willis, Gambacorti-Passerini, Volinia, Marcucci, Caligiuri, Leone, Perrotti: "Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis." in: Blood, Vol. 111, Issue 2, pp. 816-28, (2008) (PubMed).

Zhang, Huang, Yang, Greshock, Liang, Hasegawa, Giannakakis, Poulos, OBrien-Jenkins, Katsaros, Butzow, Weber, Coukos: "Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 18 Pt 1, pp. 5314-21, (2007) (PubMed).

Synonyms and alternative names related to PIK3R3

phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3), phosphoinositide-3-kinase regulatory subunit 3 (Pik3r3), phosphoinositide-3-kinase, regulatory subunit 3 (gamma) (PIK3R3), phosphoinositide-3-kinase, regulatory subunit 3b (gamma) (pik3r3b), AA414954, p55, p55-GAMMA, p55pik, pik3r3, zgc:55564, zgc:85710

Protein level used designations for PIK3R3

  • phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
  • PI3-kinase regulatory subunit gamma
  • PI3-kinase subunit p55-gamma
  • PI3K regulatory subunit gamma
  • phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma
  • phosphatidylinositol 3-kinase regulatory subunit gamma
  • ptdIns-3-kinase regulatory subunit gamma
  • ptdIns-3-kinase regulatory subunit p55-gamma
  • 100% homology to SWISS-PROT Q92569
  • p55PIK
  • phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)
  • phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)
  • phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)
  • PI3-kinase p85 subunit gamma
  • PI3-kinase subunit p85-gamma
  • phosphatidylinositol 3-kinase 85 kDa regulatory subunit gamma
  • ptdIns-3-kinase p85-gamma
  • ptdIns-3-kinase regulatory subunit p85-gamma
  • phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
  • phosphatidylinositol 3-kinase p55 subunit
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