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PIK3C3 Products

(Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Categories

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis (By similarity).

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Featured PIK3C3 Categories

PIK3C3 Antibodies

High quality antibodies with extensive validation data.

PIK3C3 ELISA Kits

Reliable ELISA kits for a wide range of species.

PIK3C3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIK3C3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7443278
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (2)
  • (4)
Cat. No. ABIN388594
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN711656
Quantity 100 μL
Datasheet Datasheet

Recommended PIK3C3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958552
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958553
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958554
Quantity 96 tests
Datasheet Datasheet

Recommended PIK3C3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315069
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509088
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416418
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PIK3C3 products

Campa, Margaria, Derle, Del Giudice, De Santis, Gozzelino, Copperi, Bosia, Hirsch: "Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes." in: Nature chemical biology, Vol. 14, Issue 8, pp. 801-810, (2018) (PubMed).

Wang, Li, Du, Xu, Wang, Zhang, Xu, Zeng, Mao, Cao: "The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex." in: Journal of pharmacological sciences, Vol. 134, Issue 4, pp. 197-202, (2018) (PubMed).

Chen, Wu, Sang, Wang, Zong, Sun, Liu, Zhao: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." in: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).

Wang, Liang, Lau, Du, Guo, Yan, Gan, Yan, Zhao, Gao, Koch, Ma: "Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling." in: Autophagy, Vol. 13, Issue 11, pp. 1855-1869, (2017) (PubMed).

Delaney, Patel, Willis, Haghighiabyaneh, Axelrod, Tancioni, Lu, Bapat, Young, Cadassou, Bartakova, Sheth, Haft, Hui, Saenz, Schlaepfer, Harismendy, Stupack: "Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer." in: Nature communications, Vol. 8, pp. 14423, (2017) (PubMed).

Won, Yen, Lin, Jiang-Shieh, Lin, Chen, Su: "Autophagy mediates cytotoxicity of human colorectal cancer cells treated with garcinielliptone FC." in: Journal of cellular physiology, Vol. 233, Issue 1, pp. 497-505, (2017) (PubMed).

Lin, Wang, Hsu, Cho, Yang, Chien: "Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway." in: International journal of molecular sciences, Vol. 18, Issue 7, (2017) (PubMed).

Marcel, Sarin: "Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells." in: eLife, Vol. 5, (2016) (PubMed).

Liu, Ji, Zhou, Xing: "Phosphatidylinositol 3-Kinase Promotes Activation and Vacuolar Acidification and Delays Methyl Jasmonate-Induced Leaf Senescence." in: Plant physiology, Vol. 170, Issue 3, pp. 1714-31, (2016) (PubMed).

Brigger, Schläfli, Garattini, Tschan: "Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity." in: Cell death & disease, Vol. 6, pp. e1861, (2015) (PubMed).

Synonyms and alternative names related to PIK3C3

phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3), phosphatidylinositol 3-kinase catalytic subunit type 3 L homeolog (pik3c3.L), phosphatidylinositol 3-kinase, catalytic subunit type 3 (pik3c3), phosphatidylinositol 3-kinase, catalytic subunit type 3 (Pik3c3), phosphatidylinositol 3-kinase catalytic subunit type 3 (Pik3c3), 5330434F23Rik, hVps34, im:7147158, VPS34, Vps34, wu:fc13g06, wu:fz51e12, zgc:112016, zgc:113009

Protein level used designations for PIK3C3

  • phosphoinositide-3-kinase, class 3
  • phosphatidylinositol 3-kinase catalytic subunit type 3
  • PI3K type 3
  • PI3-kinase type 3
  • ptdIns-3-kinase type 3
  • phosphoinositide-3-kinase class 3
  • catalytic phosphatidylinositol 3-kinase 3
  • PtdIns-3-kinase type 3
  • phosphatidylinositol 3-kinase p100 subunit
  • class 3 phosphoinositide-3-kinase
  • PI-3K Vps34p
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