PIK3C3 Products
(Phosphoinositide-3-Kinase, Class 3 (PIK3C3))
Categories
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis (By similarity).
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Featured PIK3C3 Categories
PIK3C3 Antibodies
High quality antibodies with extensive validation data.
PIK3C3 ELISA Kits
Reliable ELISA kits for a wide range of species.
PIK3C3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PIK3C3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7443278
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (2)
- (4)
Cat. No.
ABIN388594
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN711656
Quantity
100 μL
Datasheet
Datasheet
Recommended PIK3C3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958552
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958553
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958554
Quantity
96 tests
Datasheet
Datasheet
Recommended PIK3C3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315069
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509088
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7416418
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PIK3C3 products
: "Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes." in: Nature chemical biology, Vol. 14, Issue 8, pp. 801-810, (2018) (PubMed).: "The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex." in: Journal of pharmacological sciences, Vol. 134, Issue 4, pp. 197-202, (2018) (PubMed).
: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." in: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).
: "Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling." in: Autophagy, Vol. 13, Issue 11, pp. 1855-1869, (2017) (PubMed).
: "Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer." in: Nature communications, Vol. 8, pp. 14423, (2017) (PubMed).
: "Autophagy mediates cytotoxicity of human colorectal cancer cells treated with garcinielliptone FC." in: Journal of cellular physiology, Vol. 233, Issue 1, pp. 497-505, (2017) (PubMed).
: "Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway." in: International journal of molecular sciences, Vol. 18, Issue 7, (2017) (PubMed).
: "Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells." in: eLife, Vol. 5, (2016) (PubMed).
: "Phosphatidylinositol 3-Kinase Promotes Activation and Vacuolar Acidification and Delays Methyl Jasmonate-Induced Leaf Senescence." in: Plant physiology, Vol. 170, Issue 3, pp. 1714-31, (2016) (PubMed).
: "Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity." in: Cell death & disease, Vol. 6, pp. e1861, (2015) (PubMed).
Synonyms and alternative names related to PIK3C3
phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3), phosphatidylinositol 3-kinase catalytic subunit type 3 L homeolog (pik3c3.L), phosphatidylinositol 3-kinase, catalytic subunit type 3 (pik3c3), phosphatidylinositol 3-kinase, catalytic subunit type 3 (Pik3c3), phosphatidylinositol 3-kinase catalytic subunit type 3 (Pik3c3), 5330434F23Rik, hVps34, im:7147158, VPS34, Vps34, wu:fc13g06, wu:fz51e12, zgc:112016, zgc:113009Protein level used designations for PIK3C3
- phosphoinositide-3-kinase, class 3
- phosphatidylinositol 3-kinase catalytic subunit type 3
- PI3K type 3
- PI3-kinase type 3
- ptdIns-3-kinase type 3
- phosphoinositide-3-kinase class 3
- catalytic phosphatidylinositol 3-kinase 3
- PtdIns-3-kinase type 3
- phosphatidylinositol 3-kinase p100 subunit
- class 3 phosphoinositide-3-kinase
- PI-3K Vps34p
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