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PICK1 Products

(Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

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The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured PICK1 Categories

PICK1 Antibodies

High quality antibodies with extensive validation data.

PICK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PICK1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PICK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, IF
Validations
  • (5)
Cat. No. ABIN7257176
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7164283
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN185725
Quantity 100 μg
Datasheet Datasheet

Recommended PICK1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958917
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116759
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116760
Quantity 96 tests
Datasheet Datasheet

Recommended PICK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315005
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315003
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5623695
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PICK1 products

Li, Wang, Yao, Jin, Qian, Li, Wang, Zhang, Chen, Jia, Shen, Wang: "Loss of ICA69 potentiates long-lasting hyperalgesia after subcutaneous formalin injection into the mouse hindpaw." in: Neurochemical research, Vol. 40, Issue 3, pp. 579-90, (2015) (PubMed).

Williams, Balsor, Beshara, Beston, Jones, Murphy: "Experience-dependent central vision deficits: Neurobiology and visual acuity." in: Vision research, (2015) (PubMed).

Wang, Zhou, Li, Wang, Li, Zhang, Wang, Liu, Shen: "Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 16, pp. 6429-43, (2015) (PubMed).

Pandey, Rai, Gaur, Prasad: "Development- and age-related alterations in the expression of AMPA receptor subunit GluR2 and its trafficking proteins in the hippocampus of male mouse brain." in: Biogerontology, Vol. 16, Issue 3, pp. 317-28, (2015) (PubMed).

Rocca, Hanley: "PICK1 links AMPA receptor stimulation to Cdc42." in: Neuroscience letters, Vol. 585, pp. 155-9, (2014) (PubMed).

Ghasemzadeh, Vasudevan, Mueller, Seubert, Mantsch: "Region-specific alterations in glutamate receptor expression and subcellular distribution following extinction of cocaine self-administration." in: Brain research, Vol. 1267, pp. 89-102, (2014) (PubMed).

Pinheiro, Jansen, de Wit, Tawfik, Madsen, Verhage, Gether, Sørensen: "The BAR domain protein PICK1 controls vesicle number and size in adrenal chromaffin cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 32, pp. 10688-700, (2014) (PubMed).

Hoy, Haeger, Constable, Arias, McCallum, Kyweriga, Davis, Schnell, Wehr, Castillo, Washbourne: "Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 22, pp. 9364-84, (2013) (PubMed).

Anggono, Koç-Schmitz, Widagdo, Kormann, Quan, Chen, Robinson, Choi, Linden, Plomann, Huganir: "PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 34, pp. 13976-81, (2013) (PubMed).

Wang, Wang, Sun, Yang, Su, Xie, Zhou, Wang, Shen: "C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKC? complex and cerebellar plasticity." in: PLoS ONE, Vol. 8, Issue 12, pp. e83862, (2013) (PubMed).

Synonyms and alternative names related to PICK1

protein interacting with PRKCA 1 (PICK1), protein interacting with C kinase 1 (Pick1), protein interacting with PRKCA 1 (Pick1), protein interacting with PRKCA 1 (pick1), protein interacting with PRKCA 1 L homeolog (pick1.L), DKFZp470L2127, MGC131295, PICK, PICK1, PRKCABP, Prkcabp, prkcabp

Protein level used designations for PICK1

  • PRKCA-binding protein
  • protein interacting with C kinase 1
  • protein kinase C-alpha-binding protein
  • protein kinase C, alpha binding protein
  • protein that interacts with C kinase 1
  • protein interacting with PRKCA 1
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