PI3 Products
(Peptidase Inhibitor 3, Skin-Derived (PI3))
Categories
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2008].
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Featured PI3 Categories
PI3 Antibodies
High quality antibodies with extensive validation data.
PI3 ELISA Kits
Reliable ELISA kits for a wide range of species.
PI3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PI3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
IHC
Validations
- (4)
Cat. No.
ABIN7256144
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (3)
Cat. No.
ABIN948256
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6145588
Quantity
100 μL
Datasheet
Datasheet
Recommended PI3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958441
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962602
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1672903
Quantity
96 tests
Datasheet
Datasheet
Recommended PI3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314969
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293T Cells
Validations
- (1)
Cat. No.
ABIN4369875
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN1097697
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PI3 products
: "Serum alarm antiproteases in systemic sclerosis patients." in: Human immunology, Vol. 78, Issue 9, pp. 559-564, (2018) (PubMed).: "Matrix stiffness exerts biphasic control over monocyte-endothelial adhesion via Rho-mediated ICAM-1 clustering." in: Integrative biology : quantitative biosciences from nano to macro, Vol. 8, Issue 8, pp. 869-78, (2016) (PubMed).
: "Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models." in: The British journal of dermatology, (2016) (PubMed).
: "Neutrophil serine proteases and their endogenous inhibitors in coronary artery ectasia patients." in: Anatolian journal of cardiology, Vol. 16, Issue 1, pp. 23-8, (2016) (PubMed).
: "Serine protease inhibitors protect better than IL-10 and TGF-? anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci." in: Microbial cell factories, Vol. 14, pp. 26, (2015) (PubMed).
: "Fulminant skin GvHD with a cytokine pattern resemblant of cytokine release syndrome successfully treated with multimodal immunosuppression including tocilizumab." in: Pediatric blood & cancer, Vol. 62, Issue 11, pp. 2033-5, (2015) (PubMed).
: "Profiling post-centrifugation delay of serum and plasma with antibody bead arrays." in: Journal of proteomics, Vol. 95, pp. 46-54, (2013) (PubMed).
: "The impact of salt water soaks on biophysical and molecular parameters in psoriatic epidermis equivalents." in: Dermatology (Basel, Switzerland), Vol. 223, Issue 3, pp. 230-8, (2012) (PubMed).
: "Elafin selectively regulates the sensitivity of ovarian cancer cells to genotoxic drug-induced apoptosis." in: Gynecologic oncology, Vol. 125, Issue 3, pp. 727-33, (2012) (PubMed).
: "Dynamic alteration of human beta-defensin 2 localization from cytoplasm to intercellular space in psoriatic skin." in: Journal of molecular medicine (Berlin, Germany), Vol. 80, Issue 10, pp. 678-84, (2002) (PubMed).
Synonyms and alternative names related to PI3
peptidase inhibitor 3 (PI3), peptidase inhibitor 3, skin-derived (SKALP) (PI3), cementoin, elafin, ESI, SKALP, trappin-2, TRAPPIN-2, WAP3, WFDC14Protein level used designations for PI3
- PI-3
- WAP four-disulfide core domain 14
- WAP four-disulfide core domain protein 14
- elafin
- elastase-specific inhibitor
- pre-elafin
- protease inhibitor 3, skin-derived (SKALP)
- protease inhibitor WAP3
- skin-derived antileukoproteinase
- trappin-2
- elafin preproprotein
- peptidase inhibitor 3, skin-derived (SKALP)
- TRAPPIN-2 protein
- trappin ovine homolog
- peptidase inhibitor 3, skin-derived
- trappin 8
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