Phospholipase C gamma 1 Products
(phospholipase C, gamma 1 (PLCG1))
Categories
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured Phospholipase C gamma 1 Categories
Phospholipase C gamma 1 Antibodies
High quality antibodies with extensive validation data.
Phospholipase C gamma 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Phospholipase C gamma 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Phospholipase C gamma 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (1)
- (7)
Cat. No.
ABIN562265
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (7)
Cat. No.
ABIN7431485
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (6)
Cat. No.
ABIN6256799
Quantity
100 μL
Datasheet
Datasheet
Recommended Phospholipase C gamma 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN6730785
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969307
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958575
Quantity
96 tests
Datasheet
Datasheet
Recommended Phospholipase C gamma 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315336
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7389746
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN2967705
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Phospholipase C gamma 1 products
: "Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone." in: Nature communications, Vol. 7, pp. 13885, (2018) (PubMed).: "mTORC1 activation downregulates FGFR3 and PTH/PTHrP receptor in articular chondrocytes to initiate osteoarthritis." in: Osteoarthritis and cartilage, Vol. 25, Issue 6, pp. 952-963, (2018) (PubMed).
: "Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells." in: Oncotarget, Vol. 8, Issue 51, pp. 88630-88644, (2017) (PubMed).
: "PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras." in: Science signaling, Vol. 6, Issue 304, pp. ra105, (2013) (PubMed).
: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).
: "Signal regulatory protein ? negatively regulates mast-cell activation following Fc?RI aggregation." in: European journal of immunology, Vol. 43, Issue 6, pp. 1598-607, (2013) (PubMed).
: "Down-regulation of miR-218-2 and its host gene SLIT3 cooperate to promote invasion and progression of thyroid cancer." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 8, pp. E1334-44, (2013) (PubMed).
: "Inhibition of vascular smooth muscle cell proliferation by the vitamin E derivative pentamethylhydroxychromane in an in vitro and in vivo study: pivotal role of hydroxyl radical-mediated PLCgamma1 ..." in: Free radical biology & medicine, Vol. 49, Issue 5, pp. 881-93, (2010) (PubMed).
: "Multiple host proteins that function in phosphatidylinositol-4-phosphate metabolism are recruited to the chlamydial inclusion." in: Infection and immunity, Vol. 78, Issue 5, pp. 1990-2007, (2010) (PubMed).
: "CCR7/CCL21 migration on fibronectin is mediated by phospholipase Cgamma1 and ERK1/2 in primary T lymphocytes." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 38781-7, (2010) (PubMed).
Synonyms and alternative names related to Phospholipase C gamma 1
phospholipase C gamma 1 (PLCG1), phospholipase C gamma 1 L homeolog (plcg1.L), 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (LOC100633163), phospholipase C, gamma 1 (Plcg1), phospholipase C gamma 1 (Plcg1), phospholipase C, gamma 1 (plcg1), AI894140, Cded, fj46f04, NCKAP3, nckap3, Plc-1, Plc-gamma1, PLC-II, plc-ii, PLC1, plc1, PLC148, plc148, Plcg-1, PLCgamma1, plcgamma1, PPLCA, wu:fj46f04, wu:fj57a05Protein level used designations for Phospholipase C gamma 1
- 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1
- PLC-148
- PLC-gamma-1
- inositoltrisphosphohydrolase
- monophosphatidylinositol phosphodiesterase
- phosphatidylinositol phospholipase C
- phosphoinositidase C
- phosphoinositide phospholipase C
- phosphoinositide phospholipase C-gamma-1
- phospholipase C, gamma 1 (formerly subtype 148)
- phospholipase C-148
- phospholipase C-II
- phospholipase C-gamma-1
- triphosphoinositide phosphodiesterase
- PLC gamma 1
- phospholipase C-gamma-1b
- phospholipase C, gamma 1
- PLC-II
- cell differentiation and embryonic development
- dead beat
- ded
Did you look for something else?
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- Phospholipase D
- Phospholipase D2
- Phospholipase D4
- Phospholipid-binding Lipoprotein mlaA
- phosphoribosyl Pyrophosphate Synthetase 1
- Phosphorylase A
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- Phosphorylase, Glycogen, Muscle
- Phosphoserine
- Phosphothreonine
- Phosphotransacetylase
- Phosphotyrosine
- Photoreceptor Cell Specific Nuclear Receptor
- PHOX2A
- PHOX2B
- PHPT1
- PHRF1
- PHTF1
- PHTF2
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