Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Phospholamban Products

(Phospholamban (PLN))
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured Phospholamban Categories

Phospholamban Antibodies

High quality antibodies with extensive validation data.

Phospholamban ELISA Kits

Reliable ELISA kits for a wide range of species.

Phospholamban Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Phospholamban Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7442687
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC, FACS
Validations
  • (5)
Cat. No. ABIN3032226
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN682468
Quantity 100 μL
Datasheet Datasheet

Recommended Phospholamban ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969290
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958555
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1571936
Quantity 96 tests
Datasheet Datasheet

Recommended Phospholamban Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315443
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7412563
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395149
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Phospholamban products

Jin, Nesbitt, Yang, Chen, Horowitz, Jones, Vandergaast, Carey, Reiter, Russell, Kyratsous, Hooper, Hamilton, Ferreira, Deng, Straus, Baras, Hillyer, Luchsinger: "Seroprevalence of anti-SARS-CoV-2 antibodies in a cohort of New York City metro blood donors using multiple SARS-CoV-2 serological assays: Implications for controlling the epidemic and "Reopening"." in: PloS one, Vol. 16, Issue 4, pp. e0250319, (2021) (PubMed).

Stathopoulou, Schobesberger, Bork, Sprenger, Perera, Sotoud, Geertz, David, Christ, Nikolaev, Cuello: "Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes." in: Cellular signalling, Vol. 63, pp. 109362, (2019) (PubMed).

Kushnir, Santulli, Reiken, Coromilas, Godfrey, Brunjes, Colombo, Yuzefpolskaya, Sokol, Kitsis, Marks: "Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure." in: Circulation, Vol. 138, Issue 11, pp. 1144-1154, (2019) (PubMed).

Rigatti, Le, Gerber, Moraru, Dodge-Kafka: "Phosphorylation state-dependent interaction between AKAP7δ/γ and phospholamban increases phospholamban phosphorylation." in: Cellular signalling, Vol. 27, Issue 9, pp. 1807-15, (2015) (PubMed).

Kienesberger, Pulinilkunnil, Sung, Nagendran, Haemmerle, Kershaw, Young, Light, Oudit, Zechner, Dyck: "Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction." in: Molecular and cellular biology, Vol. 32, Issue 4, pp. 740-50, (2012) (PubMed).

Møller, Pham, Gustafsson, Hedley, Ersbøll, Bundgaard, Andersen, Torp-Pedersen, Køber, Christiansen: "The role of Lamin A/C mutations in Danish patients with idiopathic dilated cardiomyopathy." in: European journal of heart failure, Vol. 11, Issue 11, pp. 1031-5, (2009) (PubMed).

Prasad, Inesi: "Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes." in: American journal of physiology. Cell physiology, Vol. 296, Issue 5, pp. C992-C1002, (2009) (PubMed).

Pantos, Mourouzis, Markakis, Dimopoulos, Xinaris, Kokkinos, Panagiotou, Cokkinos: "Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 32, Issue 2, pp. 333-9, (2007) (PubMed).

Rodriguez, Kranias: "Phospholamban: a key determinant of cardiac function and dysfunction." in: Archives des maladies du coeur et des vaisseaux, Vol. 98, Issue 12, pp. 1239-43, (2006) (PubMed).

Kaliman, Catalucci, Lam, Kondo, Gutiérrez, Reddy, Palacín, Zorzano, Chien, Ruiz-Lozano: "Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8016-21, (2005) (PubMed).

Synonyms and alternative names related to Phospholamban

phospholamban (PLN), phospholamban (pln), phospholamban (Pln), cmd1p, CMD1P, CMH18, LOC100226261, plb, PLB, Plb, Plm

Protein level used designations for Phospholamban

  • phospholamban
  • cardiac phospholamban
  • PLB
You are here:
Support