PHLDA3 Products
(Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
Categories
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor (By similarity).
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Featured PHLDA3 Categories
PHLDA3 Antibodies
High quality antibodies with extensive validation data.
PHLDA3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PHLDA3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7247396
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN2452076
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, WB
Validations
- (1)
Cat. No.
ABIN7187767
Quantity
100 μg
Datasheet
Datasheet
Recommended PHLDA3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314936
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314938
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3085960
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PHLDA3 products
: "PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt." in: Cell, Vol. 136, Issue 3, pp. 535-50, (2009) (PubMed).: "A novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 10, Issue 12, pp. 1150-9, (2000) (PubMed).
Synonyms and alternative names related to PHLDA3
pleckstrin homology like domain family A member 3 (PHLDA3), pleckstrin homology like domain, family A, member 3 (Phlda3), pleckstrin homology-like domain, family A, member 3 (Phlda3), pleckstrin homology-like domain, family A, member 3 (phlda3), si:dz182n13.5, TIH1, Tih1, zgc:92333Protein level used designations for PHLDA3
- pleckstrin homology-like domain, family A, member 3
- TDAG51/Ipl homolog 1
- pleckstrin homology-like domain family A member 3
- pleckstrin homology-like domain, family A, member 2
- TDAG/lpl homolog 1
Did you look for something else?
- PHLDA2
- PHLDA1
- PHKG2
- PHKG1
- PHKB
- PHKA2
- PHKA1
- PHIP
- PHGDH
- PHF8
- PHF7
- PHF6
- PHF5A
- PHF3
- PHF23
- PHF21B
- PHF21A
- PHF20L1
- PHF20
- PHF2
- PHLDB1
- PHLDB2
- PHLDB3
- PHLPP1
- PHLPP2
- PHNC2
- PHO85
- Phosducin
- Phosducin-Like
- Phosphatase and Actin Regulator 3
- Phosphatase and Actin Regulator 4
- Phosphatase and Tensin Homolog
- Phosphate Cytidylyltransferase 1, Choline, alpha
- Phosphate Cytidylyltransferase 1, Choline, beta
- Phosphate-Binding Protein PstS 1
- Phosphatidylinositol Antibody IgG/IgM
- Phosphatidylinositol Binding clathrin Assembly Protein
- Phosphatidylinositol Phosphate
- Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta
- Phospho Protein Kinase C
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