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PHLDA2 Products

(Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))
This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver. [provided by RefSeq, Oct 2010].

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Featured PHLDA2 Categories

PHLDA2 Antibodies

High quality antibodies with extensive validation data.

PHLDA2 ELISA Kits

Reliable ELISA kits for a wide range of species.

PHLDA2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PHLDA2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN563272
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7439669
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7163670
Quantity 100 μL
Datasheet Datasheet

Recommended PHLDA2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116589
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116590
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN512298
Quantity 96 tests
Datasheet Datasheet

Recommended PHLDA2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314934
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7318893
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405600
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PHLDA2 products

Yan, Tang, Zhang, He, Huang, Zhang, Meng, Guo, Lv, Guo: "TSSC3 represses self-renewal of osteosarcoma stem cells and Nanog expression by inhibiting the Src/Akt pathway." in: Oncotarget, Vol. 8, Issue 49, pp. 85628-85641, (2017) (PubMed).

Jin, Qiao, Luan, Li: "Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis." in: International journal of molecular medicine, Vol. 37, Issue 4, pp. 949-57, (2016) (PubMed).

Jin, Qiao, Luan, Shang et al.: "The expression of the imprinted gene pleckstrin homology-like domain family A member 2 in placental tissues of preeclampsia and its effects on the proliferation, migration and invasion of trophoblast ..." in: Clinical and experimental pharmacology & physiology, Vol. 42, Issue 11, pp. 1142-51, (2015) (PubMed).

Suzuki, Shaw, Kaneko-Ishino, Ishino, Renfree: "Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting." in: BMC evolutionary biology, Vol. 11, pp. 244, (2011) (PubMed).

Dai, Huang, Li, Meng, Wang, Guo: "TSSC3 overexpression associates with growth inhibition, apoptosis induction and enhances chemotherapeutic effects in human osteosarcoma." in: Carcinogenesis, Vol. 33, Issue 1, pp. 30-40, (2011) (PubMed).

Qian, Frank, OKeefe, Dao, Zhao, Yuan, Wang, Keating, Walsh, Tycko: "The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis." in: Human molecular genetics, Vol. 6, Issue 12, pp. 2021-9, (1997) (PubMed).

Synonyms and alternative names related to PHLDA2

pleckstrin homology like domain family A member 2 (PHLDA2), Pleckstrin homology-like domain family A member 2 (phla2), pleckstrin homology like domain, family A, member 2 (Phlda2), pleckstrin homology-like domain, family A, member 2 (Phlda2), pleckstrin homology like domain family A member 2 (Phlda2), pleckstrin homology-like domain, family A, member 2 L homeolog (phlda2.L), pleckstrin homology-like domain, family A, member 2 (phlda2), BRW1C, BWR1C, HLDA2, ipl, IPL, Ipl, PHLDA2, phlda2, TSSC3, Tssc3, zgc:110459

Protein level used designations for PHLDA2

  • pleckstrin homology-like domain, family A, member 2
  • pleckstrin homology-like domain family A member 2
  • Imprinted in placenta and liver protein
  • beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein
  • imprinted in placenta and liver protein
  • p17-BWR1C
  • p17-Beckwith-Wiedemann region 1 C
  • p17-Beckwith-Wiedemann region 1C
  • tumor suppressing subchromosomal transferable fragment cDNA 3
  • tumor suppressing subtransferable candidate 3
  • tumor-suppressing STF cDNA 3 protein
  • tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein
  • tumor-supressing STF cDNA 3
  • protein 50C15
  • tumor-suppressing subchromosomal transferable fragment 3
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