PHKA1 Products
(phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))
Categories
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.[provided by RefSeq, Feb 2010].
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Featured PHKA1 Categories
PHKA1 Antibodies
High quality antibodies with extensive validation data.
PHKA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PHKA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PHKA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN2856675
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN562210
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7163404
Quantity
100 μg
Datasheet
Datasheet
Recommended PHKA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1148075
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1148076
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1148078
Quantity
96 tests
Datasheet
Datasheet
Recommended PHKA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314914
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093469
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3133202
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PHKA1 products
: "A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation." in: Cellular and molecular life sciences : CMLS, (2015) (PubMed).: "Alpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle." in: Human molecular genetics, Vol. 19, Issue 7, pp. 1335-46, (2010) (PubMed).
Synonyms and alternative names related to PHKA1
phosphorylase kinase regulatory subunit alpha 1 (PHKA1), phosphorylase kinase, alpha 1a (muscle) (phka1a), phosphorylase kinase, alpha 1 (muscle) (phka1), phosphorylase kinase alpha 1 (Phka1), phosphorylase kinase regulatory subunit alpha 1 (Phka1), phosphorylase kinase, alpha 1 (muscle) (PHKA1), 5330411D17, 9830108K24Rik, Pcyt1b, Phka, PHKA, PHKA1, wu:fl37h01Protein level used designations for PHKA1
- phosphorylase kinase, alpha 1 (muscle)
- phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform
- phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform-like
- phosphorylase kinase alpha M subunit
- Phosphorylase kinase alpha M subunit
- PhK-alpha-subunit
- phosphorylase B kinase alpha subunit
- phosphorylase kinase alpha-subunit
- phosphorylase b kinase regulatory subunit alpha skeletal muscle isoform
- phosphorylase kinase, alpha 1 (muscle), muscle glycogenosis
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