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PHF8 Products

(PHD Finger Protein 8 (PHF8))
The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].

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Featured PHF8 Categories

PHF8 Antibodies

High quality antibodies with extensive validation data.

PHF8 ELISA Kits

Reliable ELISA kits for a wide range of species.

PHF8 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PHF8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7269263
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rabbit
Application WB, IHC, IP, IF, IHC (p), ChIP, PLA
Validations
  • (1)
Cat. No. ABIN2626773
Quantity 50 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1869797
Quantity 100 μL
Datasheet Datasheet

Recommended PHF8 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958513
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674795
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5657750
Quantity 96 tests
Datasheet Datasheet

Recommended PHF8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Baculovirus
Validations
  • (2)
Cat. No. ABIN2669683
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408999
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094532
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PHF8 products

Chen, Wang, Zhou, Han, Li, Xu, Xu, Zhu, Deng, Yu, Song, Chen, Song, Takahashi, He, He, Li, Chen: "Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway." in: Nature communications, Vol. 9, Issue 1, pp. 114, (2018) (PubMed).

Tong, Liu, Liu, Yuan, Wang, Guo, Lan, Zhang, Dong, Wang, Xiao, Mu, Mao, Wong, Jiang: "The HIF/PHF8/AR axis promotes prostate cancer progression." in: Oncogenesis, Vol. 5, Issue 12, pp. e283, (2016) (PubMed).

Zhu, Wang, Li, Wang, Xu, Wang, Sun, Dong, Chen, Mao, Yu, Li, Li, Chen, Chen: "PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis." in: Cell research, Vol. 20, Issue 7, pp. 794-801, (2010) (PubMed).

Qi, Sarkissian, Hu, Wang, Bhattacharjee, Gordon, Gonzales, Lan, Ongusaha, Huarte, Yaghi, Lim, Garcia, Brizuela, Zhao, Roberts, Shi: "Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development." in: Nature, Vol. 466, Issue 7305, pp. 503-7, (2010) (PubMed).

Synonyms and alternative names related to PHF8

PHD finger protein 8 (Phf8), PHD finger protein 8 (PHF8), PHD finger protein 8 (phf8), 9830141C09Rik, JHDM1F, mKIAA1111, MRXSSD, RGD1561065, ZNF422, zPHF8

Protein level used designations for PHF8

  • histone lysine demethylase PHF8
  • jumonji C domain-containing histone demethylase 1F
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