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PGRMC1 Products

(Progesterone Receptor Membrane Component 1 (PGRMC1))

Categories

This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010].

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Featured PGRMC1 Categories

PGRMC1 Antibodies

High quality antibodies with extensive validation data.

PGRMC1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PGRMC1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN185610
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, FACS, ICC
Validations
  • (7)
Cat. No. ABIN5542351
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (10)
Cat. No. ABIN6145520
Quantity 100 μL
Datasheet Datasheet

Recommended PGRMC1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975743
Quantity 96 tests
Datasheet Datasheet

Recommended PGRMC1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314839
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314841
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2728798
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our PGRMC1 products

Zhang, Xia, Wang, Zhang, Lu, Yu, Deng, Yang, Zhu, Xu, Liang: "PGRMC1 Is a Novel Potential Tumor Biomarker of Human Renal Cell Carcinoma Based on Quantitative Proteomic and Integrative Biological Assessments." in: PLoS ONE, Vol. 12, Issue 1, pp. e0170453, (2017) (PubMed).

Kabe, Nakane, Koike, Yamamoto, Sugiura, Harada, Sugase, Shimamura, Ohmura, Muraoka, Yamamoto, Uchida, Iwata, Yamaguchi, Krayukhina, Noda, Handa, Ishimori, Uchiyama, Kobayashi, Suematsu: "Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance." in: Nature communications, Vol. 7, pp. 11030, (2016) (PubMed).

Izzo, Xu, Zeng, Kirk, Mozzoni, Silky, Rehak, Yurko, Look, Rishton, Safferstein, Cruchaga, Goate, Cahill, Arancio, Mach, Craven, Head, LeVine, Spires-Jones, Catalano: "Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity." in: PLoS ONE, Vol. 9, Issue 11, pp. e111899, (2015) (PubMed).

Allen, Feng, Grotegut, Murtha: "Progesterone receptor membrane component 1 as the mediator of the inhibitory effect of progestins on cytokine-induced matrix metalloproteinase 9 activity in vitro." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 21, Issue 2, pp. 260-8, (2014) (PubMed).

He, Cattran, Nguyen, Nieminen, Xu: "Triple-responsive expansile nanogel for tumor and mitochondria targeted photosensitizer delivery." in: Biomaterials, Vol. 35, Issue 35, pp. 9546-53, (2014) (PubMed).

Thomas, Pang, Dong et al.: "Enhancement of cell surface expression and receptor functions of membrane progestin receptor α (mPRα) by progesterone receptor membrane component 1 (PGRMC1): evidence for a role of PGRMC1 as an ..." in: Endocrinology, Vol. 155, Issue 3, pp. 1107-19, (2014) (PubMed).

Peluso, Yuan, Liu, Lodde et al.: "Plasminogen activator inhibitor 1 RNA-binding protein interacts with progesterone receptor membrane component 1 to regulate progesterone's ability to maintain the viability of spontaneously ..." in: Biology of reproduction, Vol. 88, Issue 1, pp. 20, (2013) (PubMed).

Hulce, Cognetta, Niphakis, Tully, Cravatt: "Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells." in: Nature methods, Vol. 10, Issue 3, pp. 259-64, (2013) (PubMed).

Bali, Arimoto, Morgan, Finch: "Progesterone antagonism of neurite outgrowth depends on microglial activation via Pgrmc1/S2R." in: Endocrinology, Vol. 154, Issue 7, pp. 2468-80, (2013) (PubMed).

Bali, Arimoto, Iwata, Lin, Zhao, Brinton, Morgan, Finch et al.: "Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17β-estradiol and progesterone in hippocampal subregions that support ..." in: Endocrinology, Vol. 153, Issue 2, pp. 759-69, (2012) (PubMed).

Synonyms and alternative names related to PGRMC1

progesterone receptor membrane component 1 (pgrmc1), progesterone receptor membrane component 1 (PGRMC1), progesterone receptor membrane component 1 (Pgrmc1), 25-Dx, 25Dx, AA415812, DKFZp469D0815, HPR6.6, MGC89150, MPR, PPMR, Vema, VEMA, wu:fa94d03, zgc:103577

Protein level used designations for PGRMC1

  • progesterone receptor membrane component 1
  • fa94d03
  • membrane-associated progesterone receptor component 1
  • progesterone binding protein
  • steroid membrane binding protein
  • acidic 25 kDa protein
  • membrane-bound progesterone receptor
  • ventral midline antigen
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