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PFKFB3 Products

(6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))

Categories

Synthesis and degradation of fructose 2,6-bisphosphate (By similarity).

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Featured PFKFB3 Categories

PFKFB3 Antibodies

High quality antibodies with extensive validation data.

PFKFB3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PFKFB3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (3)
  • (4)
Cat. No. ABIN518808
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN6145485
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (7)
  • (3)
Cat. No. ABIN392768
Quantity 400 μL
Datasheet Datasheet

Recommended PFKFB3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964498
Quantity 96 tests
Datasheet Datasheet

Recommended PFKFB3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314740
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314738
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7319866
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PFKFB3 products

Heydasch, Kessler, Warnke, Eschrich, Scholz, Bigl: "Functional diversity of PFKFB3 splice variants in glioblastomas." in: PloS one, Vol. 16, Issue 7, pp. e0241092, (2021) (PubMed).

Reid, Lowman, Pan, Tran, Warmoes, Ishak Gabra, Yang, Locasale, Kong: "IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3." in: Genes & development, Vol. 30, Issue 16, pp. 1837-51, (2016) (PubMed).

Lee, Lee, Yun, Jang, Kang, Kim, Choi, Park: "Silver nanoparticles affect glucose metabolism in hepatoma cells through production of reactive oxygen species." in: International journal of nanomedicine, Vol. 11, pp. 55-68, (2016) (PubMed).

Lv, Zhang, Zhai, Qiu, Zhang, Yao, Zhang: "PFKFB3-mediated glycolysis is involved in reactive astrocyte proliferation after oxygen-glucose deprivation/reperfusion and is regulated by Cdh1." in: Neurochemistry international, Vol. 91, pp. 26-33, (2016) (PubMed).

Fu, Shi, Westaway, Jhamandas: "Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity." in: The Journal of biological chemistry, Vol. 290, Issue 20, pp. 12504-13, (2015) (PubMed).

Ohmura, Hishiki, Yamamoto, Nakanishi, Kubo, Tsuchihashi, Tamada, Toue, Kabe, Saya, Suematsu: "Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry." in: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, Vol. 46, pp. 102-13, (2015) (PubMed).

Yamamoto, Takano, Ishiwata, Ohmura, Nagahata, Matsuura, Kamata, Sakamoto, Nakanishi, Kubo, Hishiki, Suematsu: "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway." in: Nature communications, Vol. 5, pp. 3480, (2014) (PubMed).

Bao, Mukai, Hishiki, Kubo, Ohmura, Sugiura, Matsuura, Nagahata, Hayakawa, Yamamoto, Fukuda, Saya, Suematsu, Minamishima: "Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo." in: Molecular cancer research : MCR, Vol. 11, Issue 9, pp. 973-85, (2013) (PubMed).

De Bock, Georgiadou, Schoors, Kuchnio, Wong, Cantelmo, Quaegebeur, Ghesquière, Cauwenberghs, Eelen, Phng, Betz, Tembuyser, Brepoels, Welti, Geudens, Segura, Cruys, Bifari, Decimo, Blanco, Wyns et al.: "Role of PFKFB3-driven glycolysis in vessel sprouting. ..." in: Cell, Vol. 154, Issue 3, pp. 651-63, (2013) (PubMed).

Guo, Li, Xu, Halim, Thomas, Woo, Huo, Chen, Sturino, Wu: "Disruption of inducible 6-phosphofructo-2-kinase impairs the suppressive effect of PPARγ activation on diet-induced intestine inflammatory response." in: The Journal of nutritional biochemistry, Vol. 24, Issue 5, pp. 770-5, (2013) (PubMed).

Synonyms and alternative names related to PFKFB3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Pfkfb3), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 S homeolog (pfkfb3.S), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (pfkfb3), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PTRG_09894), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Tsp_06710), E330010H22Rik, iPFK-2, IPFK2, PFK2, PFKFB3, uPFK-2, wu:fc31e01, zgc:73257

Protein level used designations for PFKFB3

  • 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase
  • 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase
  • 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
  • 6PF-2-K/Fru-2,6-P2ase 3
  • 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme
  • PFK/FBPase 3
  • fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase
  • iPFK-2
  • inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
  • renal carcinoma antigen NY-REN-56
  • 6PF-2-K/Fru-2,6-P2ASE brain-type isozyme
  • RB2K
  • inducible 6-phosphofructo-2-kinase
  • 6PF-2-K/Fru-2,6-P2ASE brain/placenta-type isozyme
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
  • 6-phosphofructo-2-kinase
  • fructose-2,6-biphosphatase 3
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3-like
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