Tyrosyl-tRNA Synthetase (Yars) Peptide
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- Target See all YARS (Yars) products
- YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-YARS antibody (Catalog #: ARP40472_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))
- Synonyms
- CMTDIC Peptide, TYRRS Peptide, YRS Peptide, YTS Peptide, AL024047 Peptide, AU018965 Peptide, cb204 Peptide, wu:fk52b08 Peptide, YARS Peptide, cmtdic Peptide, tyrrs Peptide, yrs Peptide, yts Peptide, CG4561 Peptide, Dmel\\CG4561 Peptide, TyrRS Peptide, anon-EST:Posey261 Peptide, dYARS Peptide, GB10789 Peptide, tyrosyl-tRNA synthetase Peptide, tyrosyl-tRNA synthetase L homeolog Peptide, tyrosyl-tRNA synthetase, putative Peptide, tyrosine--tRNA ligase Peptide, Tyrosyl-tRNA synthetase Peptide, tyrosine--tRNA ligase, cytoplasmic Peptide, YARS Peptide, Yars Peptide, yars Peptide, yars.L Peptide, MAL8P1.125 Peptide, MEFER_RS04475 Peptide, TyrRS Peptide, LOC413909 Peptide, LOC100163888 Peptide, LOC100282315 Peptide
- Background
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. Sequence Note: The RefSeq transhttp://www.ncbi.nlm.nih.gov/projects/locusXref/oho.cgi?server= REFTRACK&frm=0x66adf650&appid=0&evId=1&evIntpar=8565&evStrpar=&frmA n=EditApp LocusXref: edit YARS(8565)cript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMTDIC, TYRRS, YRS, YTS
Protein Interaction Partner: ELANE,ARF6,EIF1B,EIF6,SAP18
Protein Size: 528 - Molecular Weight
- 59 kDa
- Gene ID
- 8565
- NCBI Accession
- NM_003680, NP_003671
- UniProt
- P54577
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