Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (Middle Region) Peptide
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- Target See all UFD1L products
- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NYNEKIYELR VMETKPDKAV SIIECDMNVD FDAPLGYKEP ERQVQHEEST
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UFD1L Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
- Synonyms
- UFD1 Peptide, Ufd1 Peptide, ufd1 Peptide, wu:fc55f04 Peptide, zgc:92341 Peptide, Ufd1l Peptide, ubiquitin recognition factor in ER associated degradation 1 Peptide, ubiquitin recognition factor in ER-associated degradation 1 Peptide, ubiquitin fusion degradation 1 like (yeast) Peptide, ubiquitin recognition factor in ER associated degradation 1 S homeolog Peptide, ubiquitin fusion degradation protein 1 homolog Peptide, Ubiquitin Fusion Degradation (yeast UFD homolog) Peptide, UFD1 Peptide, Ufd1 Peptide, UFD1L Peptide, ufd1.S Peptide, ufd1l Peptide, ufd1 Peptide, EHI_125920 Peptide, LOC100166745 Peptide, LOC100635687 Peptide, LOC100648660 Peptide, ufd-1 Peptide
- Background
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The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
Alias Symbols: UFD1
Protein Interaction Partner: NPLOC4,VCP,AMFR,BIRC5,HMOX1,NPLOC4,RAE1,SELS,SVIP,UBL4A,USP13,VCP,VCPIP1
Protein Size: 307 - Molecular Weight
- 34 kDa
- Gene ID
- 7353
- NCBI Accession
- NM_005659, NP_005650
- UniProt
- Q92890
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