Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Peptide
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- Target See all UBE2L6 products
- UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2L6 antibody (Catalog #: ARP43033_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
- Synonyms
- UBE2L6 Peptide, RIG-B Peptide, UBCH8 Peptide, 2810489I21Rik Peptide, Ubce8 Peptide, Ubcm8 Peptide, UbcM8 Peptide, ubiquitin conjugating enzyme E2 L6 Peptide, ubiquitin-conjugating enzyme E2L 6 Peptide, UBE2L6 Peptide, Ube2l6 Peptide
- Background
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: MGC40331, RIG-B, UBCH8
Protein Interaction Partner: UBE3A,ARIH1,PARK2,RNF144B,RNF19A,RNF216,RNF40,SIAH2,SPEN,TRIM25,UBE3A,PARK2,RNF19A,RNF216,RNF40,SIAH2,TRIM25
Protein Size: 153 - Molecular Weight
- 18 kDa
- Gene ID
- 9246
- NCBI Accession
- NM_004223, NP_004214
- UniProt
- Q8N5D8
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