Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) (N-Term) Peptide
UBE2D2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UBE2D2 products
- UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2D2 antibody (Catalog #: ARP43007_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
- Background
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Alias Symbols: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Protein Interaction Partner: CBL,AMFR,BTRC,CBL,CNOT4,DTX3L,NEDD4,NFKBIA,PJA1,PJA2,RNF11,RNF5,UBE2D2,AMFR,APC11,BARD1,BIRC3,BTRC,CBL,CDKN1B,DDX58,DTX3L,DZIP3,EPS15,FBXL3,FBXO4,FBXO7,FBXW2,ING4,NEDD4,OTUB1,PDZRN3,PJA1,PJA2,POLL,POLM,RAF1,RNF11,RNF2,STAM2,STUB1,TRIM5,UBA6,UBASH3B,UBE3A
Protein Size: 147 - Molecular Weight
- 17 kDa
- Gene ID
- 7322
- NCBI Accession
- NM_003339, NP_003330
- UniProt
- P62837
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