Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2) (N-Term) Peptide
NPRL2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all NPRL2 products
- NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TUSC4 antibody (Catalog #: ARP50539_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
- Synonyms
- 2810446G01Rik Peptide, G21 Peptide, NPR2L Peptide, Tusc4 Peptide, npr2 Peptide, npr2l Peptide, tusc4 Peptide, NPR2 Peptide, TUSC4 Peptide, im:6900399 Peptide, zgc:153630 Peptide, nitrogen permease regulator-like 2 Peptide, NPR2 like, GATOR1 complex subunit S homeolog Peptide, NPR2 like, GATOR1 complex subunit Peptide, NPR2-like, GATOR1 complex subunit Peptide, Nprl2 Peptide, nprl2.S Peptide, NPRL2 Peptide, nprl2 Peptide
- Background
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TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs.
Alias Symbols: NPR2L, NPRL2, NPR2, TUSC4
Protein Interaction Partner: NPRL3,PRKAR1A,UBE2M
Protein Size: 380 - Molecular Weight
- 44 kDa
- Gene ID
- 10641
- NCBI Accession
- NM_006545, NP_006536
- UniProt
- Q8WTW4
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