Tetratricopeptide Repeat Domain 5 (TTC5) Peptide
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- Target See all TTC5 products
- TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TTC5 antibody (Catalog #: ARP49004_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
- Synonyms
- TTC5 Peptide, ttc5 Peptide, wu:fi33h05 Peptide, wu:fy81e07 Peptide, zgc:112059 Peptide, Strap Peptide, 5930437N14 Peptide, AW743060 Peptide, tetratricopeptide repeat domain 5 L homeolog Peptide, tetratricopeptide repeat domain 5 Peptide, ttc5.L Peptide, TTC5 Peptide, ttc5 Peptide, Ttc5 Peptide
- Background
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TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.
Alias Symbols: Strap
Protein Size: 440 - Molecular Weight
- 49 kDa
- Gene ID
- 91875
- NCBI Accession
- NM_138376, NP_612385
- UniProt
- Q8N0Z6
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