Tripartite Motif Containing 25 (TRIM25) (Middle Region) Peptide
-
- Target See all TRIM25 products
- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TPSSGDPGEH DPASTHKSTR PVKKVSKEEK KSKKPPPVPA LPSKLPTFGA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM25 Antibody(ARP58106_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
- Synonyms
- zgc:55773 Peptide, MGC130751 Peptide, EFP Peptide, RNF147 Peptide, Z147 Peptide, ZNF147 Peptide, AA960166 Peptide, AL022677 Peptide, Zfp147 Peptide, Efp Peptide, Znf147 Peptide, E3 ubiquitin/ISG15 ligase TRIM25 Peptide, tripartite motif containing 25 Peptide, E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog Peptide, microRNA 3614 Peptide, tripartite motif-containing 25 Peptide, LOC100146440 Peptide, trim25 Peptide, LOC100490741.L Peptide, TRIM25 Peptide, MIR3614 Peptide, Trim25 Peptide
- Background
-
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Alias Symbols: EFP, RNF147, Z147, ZNF147
Protein Interaction Partner: SFN,TFG,TRIM25,UBE2L6,DDX58,ERCC2,ESR1,ISG15,PITX2,RARRES3,SFN,STK38,TRIM25,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2D4,UBE2J2,UBE2L6,UBE2N
Protein Size: 630 - Molecular Weight
- 71 kDa
- Gene ID
- 7706
- NCBI Accession
- NM_005082, NP_005073
- UniProt
- Q14258
-