Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (Middle Region) Peptide
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- Target See all TREM2 products
- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FPGESESFED AHVEHSISRS LLEGEIPFPP TSILLLLACI FLIKILAASA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TREM2 Antibody(ARP49413_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
- Synonyms
- TREM-A1 Peptide, TREM-B1 Peptide, TREM2 Peptide, trem-2 Peptide, trem2a Peptide, trem2b Peptide, trem2c Peptide, TREM-2 Peptide, Trem2a Peptide, Trem2b Peptide, Trem2c Peptide, triggering receptor expressed on myeloid cells 2 Peptide, trem-like transcript 2 protein Peptide, TREM2 Peptide, trem2 Peptide, LOC100228399 Peptide, Trem2 Peptide
- Background
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The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
Alias Symbols: TREM-2, Trem2a, Trem2b, Trem2c
Protein Interaction Partner: TYROBP
Protein Size: 230 - Molecular Weight
- 25 kDa
- Gene ID
- 54209
- NCBI Accession
- NM_018965, NP_061838
- UniProt
- Q9NZC2
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