Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (C-Term) Peptide
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- Target See all TREM1 products
- TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LCPLYTSPRT VTQAPPKSTA DVSTPDSEIN LTNVTDIIRV PVFNIVILLA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TREM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
- Synonyms
- TREM1 Peptide, CD354 Peptide, TREM-1 Peptide, triggering receptor expressed on myeloid cells 1 Peptide, TREM1 Peptide, Trem1 Peptide, LOC100349504 Peptide
- Background
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This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: TREM-1, CD354
Protein Interaction Partner: TREM1,TYROBP,TREM1,TYROBP
Protein Size: 234 - Molecular Weight
- 26 kDa
- Gene ID
- 54210
- NCBI Accession
- NM_018643, NP_061113
- UniProt
- Q9NP99
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