Transcription Factor A, Mitochondrial (TFAM) Peptide
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- Target See all TFAM products
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Transcription Factor AntibodiesAM antibody (Catalog #: ARP31400_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
- Synonyms
- tcf6 Peptide, mttf1 Peptide, mttfa Peptide, tcf6l1 Peptide, tcf6l2 Peptide, tcf6l3 Peptide, mttfa-A Peptide, xl-mtTFA Peptide, MGC153358 Peptide, zgc:153358 Peptide, MTTF1 Peptide, MTTFA Peptide, TCF6 Peptide, TCF6L1 Peptide, TCF6L2 Peptide, TCF6L3 Peptide, AI661103 Peptide, Hmgts Peptide, mtTFA Peptide, tsHMG Peptide, Mttfa Peptide, transcription factor A, mitochondrial Peptide, transcription factor A, mitochondrial L homeolog Peptide, TFAM Peptide, tfam.L Peptide, tfam Peptide, Tfam Peptide
- Background
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The function remains unknown.This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: TCF6, MtTF1, mtTFA, TCF6L1, TCF6L2, TCF6L3
Protein Interaction Partner: NRF1,PNP,TFB1M,TFB2M,TFB1M,TFB2M
Protein Size: 246 - Molecular Weight
- 29 kDa
- Gene ID
- 7019
- NCBI Accession
- NM_003201, NP_003192
- UniProt
- Q00059
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