TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C) (C-Term) Peptide
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- Target See all TAF1C products
- TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))
- Protein Region
- C-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RRHRGETSET QTQSKRPKRR TQLSSTFSSF TSYLDSPDAS SAPRSQDLST
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Taf1c Antibody(ARP40130_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))
- Synonyms
- TAF1C Peptide, Tafi95 Peptide, mTAFI95 Peptide, MGC:39976 Peptide, SL1 Peptide, TAFI110 Peptide, TAFI95 Peptide, TATA-box binding protein associated factor, RNA polymerase I subunit C Peptide, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa Peptide, TATA-box binding protein associated factor, RNA polymerase I, C Peptide, TATA-box binding protein associated factor, RNA polymerase 1 subunit C Peptide, TAF1C Peptide, Taf1c Peptide
- Background
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Taf1c is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Taf1c recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
Alias Symbols: Tafi95, mTAFI95
Protein Interaction Partner: Tbp,Tbp
Protein Size: 836 - Molecular Weight
- 92 kDa
- Gene ID
- 21341
- NCBI Accession
- NM_021441, NP_067416
- UniProt
- Q6PDZ2
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