Spleen tyrosine Kinase (SYK) (Middle Region) Peptide
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- Target See all SYK products
- SYK (Spleen tyrosine Kinase (SYK))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RIKSYSFPKP GHRKSSPAQG NRQESTVSFN PYEPELAPWA ADKGPQREAL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SYK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SYK (Spleen tyrosine Kinase (SYK))
- Synonyms
- p72-Syk Peptide, Sykb Peptide, p72syk Peptide, spleen associated tyrosine kinase Peptide, spleen tyrosine kinase Peptide, syk Peptide, SYK Peptide, Syk Peptide
- Background
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This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp313N1010, FLJ25043, FLJ37489, p72-Syk
Protein Interaction Partner: CRKL,EZR,HHV4gp002,MSN,STAT1,STAT1,SYK,UBB,BLNK,BTK,CBL,CBLB,CD19,CD22,CD3E,CD79A,CD79B,CRKL,CSF2RB,CSF3R,CTTN,DBNL,DUSP3,EPOR,FCER1G,FCGR1A,FCGR2A,FGR,FYN,GAB2,GRB2,HCLS1,HNRNPU,IL2RB,ITGB2,JAK1,LAT,LAX1,LCK,LCP2,LYN,MAP4K1,MAPK3,MS4A2,NFAM1,PAG1,PIK3AP1,PIK3R1,PIK3R2,PLCG1,PLCG2,POU2AF1,PRKCA,PRKD1,PTK2,PTK2B,PTPN6,PXN,RASA1,RPS6KA1,SELPLG,SH2B2,SH3BP2,SHC1,SIT1,SLA,SLC4A1,SNCA,SRC,STAT1,STAT3,STAT5A,SYK,TLR4,TNFRSF1A,TRAF6,TUBA1A,TUBA4A,TYROBP,UBB,VAV1,VAV2,CALM1,CBL,CBLB,CD19,CD22,CD3E,CD4,CD72,CD79A,CD79B,CRKL,CSF3R,CTTN,Cbl,EPOR,FCER1G,FCGR2A,FCRL3,FGR,FYN,GRB2,HDAC1,HDAC2,HDAC3,HDAC4,HDAC6,HDAC9,ITGB2,LAT,LCK,LYN,MS4A2,PAG1,PLCG1,PLCG2,PRKD1,PTK2,PTK2B,PTPN6,PXN,RPS6KB1,RPS6KB2,SH3BP2,SIRPB1,SIT1,SLA,SP1,SRC,SYK,TRAF6,TUBA1A,TUBG1,UBC,Ubc,VAV1
Protein Size: 635 - Molecular Weight
- 72 kDa
- Gene ID
- 6850
- NCBI Accession
- NM_003177, NP_003168
- UniProt
- P43405
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