Surfeit 1 (SURF1) (N-Term) Peptide
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- Target See all SURF1 products
- SURF1 (Surfeit 1 (SURF1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GLRAAGLGRA PASAAWRSVL RVSPRPGVAW RPSRCGSSAA EASATKAEDD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SURF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SURF1 (Surfeit 1 (SURF1))
- Synonyms
- BcDNA:GH23574 Peptide, CG9943 Peptide, Dmel\\CG9943 Peptide, GB14201 Peptide, SURF1 Peptide, im:6898613 Peptide, zgc:158646 Peptide, Ab1-205 Peptide, SURF-1 Peptide, 0610010F23Rik Peptide, Surf-1 Peptide, SURFEIT 1 Peptide, Surfeit 1 Peptide, surfeit locus protein 1 Peptide, SURF1, cytochrome c oxidase assembly factor Peptide, surfeit 1 Peptide, surfeit gene 1 Peptide, Surfeit locus 1 cytochrome c oxidase biogenesis protein Peptide, Surf1 Peptide, LOC413781 Peptide, SURF1 Peptide, surf1 Peptide
- Background
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This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
Alias Symbols: -
Protein Size: 300 - Molecular Weight
- 33 kDa
- Gene ID
- 6834
- NCBI Accession
- NM_003172, NP_003163
- UniProt
- Q15526
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