Proto-oncogene tyrosine-protein kinase Src (Src) (N-Term) Peptide
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- Target See all Src products
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SRC antibody (Catalog #: ARP32475_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
- Synonyms
- AW259666 Peptide, pp60c-src Peptide, C-src1 Peptide, CG7524 Peptide, D-Src64B Peptide, D-src Peptide, DSRC64 Peptide, DSrc Peptide, DSrc64 Peptide, DSrc64B Peptide, Dm SRC1 Peptide, DmHD-358 Peptide, Dmel\CG7524 Peptide, Dsrc Peptide, Dsrc64 Peptide, Dsrc64B Peptide, HD-358 Peptide, MRE5 Peptide, SRC 64B Peptide, Src Peptide, Src1 Peptide, Src64 Peptide, c-src Peptide, dSrc Peptide, dsrc Peptide, src Peptide, src1 Peptide, src64 Peptide, src64B Peptide, src64b Peptide, ASV Peptide, SRC1 Peptide, c-SRC Peptide, p60-Src Peptide, c-Src Peptide, PP60C-SCR Peptide, SDR Peptide, SRC proto-oncogene, non-receptor tyrosine kinase Peptide, uncharacterized LOC5574802 Peptide, proto-oncogene tyrosine-protein kinase src Peptide, Rous sarcoma oncogene Peptide, Src oncogene at 64B Peptide, SRC Peptide, LOC5574802 Peptide, CpipJ_CPIJ010659 Peptide, Src Peptide, Src64B Peptide
- Target Type
- Viral Protein
- Background
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This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: ASV, SRC1, c-SRC, p60-Src
Protein Interaction Partner: E2F4,ABL1,BCAR1,BCR,CDCP1,DRD4,ERBB2,ETS1,ETS2,GJA1,GJB1,HNRNPK,KHDRBS1,MUC1,PDE4D,PDGFRB,PTK2,PTK2,PTPN2,RGS16,SHB,SHC1,SRC,ABL1,ACTN1,ADAM12,ADAM15,ADRB2,ADRB3,ADRBK1,AFAP1,AFAP1L2,AKT1,ANKRD11,ANXA1,ANXA2,AR,ARHGAP1,ARHGAP32,ARR3,ASAP1,ATP2B4,AXL,BCAR1,BCR,BMX,CAV1,CAV2,CBL,CBLC,CD2AP,CD33,CD36,CD46,CD59,CDCP1,CDH5,CDK5,CDKN1B,CEACAM1,CEACAM3,CHUK,CNTNAP1,CSK,CTNNB1,CTNND1,CTTN,DAB1,DAB2,DAG1,DAPP1,DDR2,DGKA,DGKZ,DLG4,DNM1,DNM2,DOK1,DOK2,DOK4,EFNB1,EFNB2,EGFR,EPHB2,EPS8,ERBB2,ESR1,ESR2,ETS1,ETS2,EVL,FARP2,FASLG,FGR,FHIT,FOXO1,FRS2,FYB,GAB2,GAB3,GFAP,GIT1,GJA1,GJB1,GNB2L1,GRB10,GRB2,GRIN2A,GRIN2B,GRLF1,GTF2I,GUCY2C,HLA-A,HLA-B,HNF1A,HNRNPK,HRAS,HSP90AA1,IGF1R,IKBKB,IKBKG,IL6R,INPPL1,INSR,ITGB3,JUP,KCNA5,KCNB1,KCNQ5,KDR,KHDRBS1,KIFAP3,KIT,LRP1,MAPK15,MATK,MED28,MET,MPZL1,MST1R,MUC1,MYLK,ND2,NFKBIA,NMT1,NOS2,NPHS1,NR1I2,P2RY2,PAK2,PDCD6IP,PDE6G,PDGFRB,PDPK1,PECAM1,PGR,PIK3R1,PKD1,PLCG1,PPARD,PPP2R4,PRKACA,PRKCA,PRKCD,PRKCE,PRKCH,PRKCI,PRKCZ,PRKD1,PTK2,PTK2B,PTPN1,PTPN11,PTPN18,PTPN2,PTPN21,PTPN6,PTPRA,PTPRE,PXN,RAF1,RASA1,RET,RGS16,RXRA,SH2D3C,SH3BP1,SH3PXD2A,SHB,SHC1,SKAP1,SLC9A2,SMARCB1,SMARCE1,SPTAN1,SRC,SRF,STAP2,STAT1,STAT3,STAT5A,STAT5B,STAT6,SYK,SYN1,TERT,THRA,TIAM1,TNFRSF11A,TRAF1,TRAF3,TRAF6,TRAT1,TRIP10,TRIP6,TRPC6,TRPV4,TUB,TXK,TYRO3,VCL,VIL1,WAS,WBP11,WWOX,YTHDC1,YWHAB,YWHAE,YWHAG,YWHAH,ABL1,ADRB2,ADRB3,ADRBK1,AHR,AR,ARHGAP1,ARHGAP17,ARHGAP32,ARHGAP32,ARNT,ARR3,ASAP1,ASAP2,AXL,Adrb3,BCAR1,BMX,CAV1,CAV2,CBL,CD44,CD46,CDC25C,CDC37,CDH1,CRK,CSF1R,CSK,CTNND1,DAB2,DAG1,DDR2,DOCK1,DOK1,DOK4,EFNB1,EGFR,EP300,EPHA3,EPHA4,EPHB2,EPS8,ERBB2,ESR1,ESR2,EVL,FOXO1,FYN,GAB2,GAB3,GNB2L1,GRB10,GRB2,GRIN2A,GSN,HNF1A,HSP90AA1,ITK,KHDRBS1,KIFAP3,LRP1,LYN,MAP2,MAPK8IP3,MATK,MET,MICAL1,MPZL1,MUC1,MYLK,NCOA6,ND2,PDE6G,PECAM1,PELP1,PIK3R1,PLCG1,PLD1,PLD2,PLSCR1,PRKCZ,PTK2,PTK2B,PTPN21,PTPRA,PXN,RAF1,RARA,RASA1,RET,RPL10,RPS6KB1,RPS6KB2,RXRA,SH3BP1,SHB,SKAP1,SLC9A2,SNURF,SRF,STAT1,STAT3,SYK,SYN1,THRB,TNFSF11,TRAF1,TRAF3,TRAF6,TRIP4,TRIP6,TRPC6,TRPV4,TYRO3,WAS
Protein Size: 536 - Molecular Weight
- 60 kDa
- Gene ID
- 6714
- NCBI Accession
- NM_198291, NP_938033
- UniProt
- P12931
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