Superoxide Dismutase 1, Soluble (SOD1) Peptide
SOD1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all SOD1 products
- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SOD1 antibody (Catalog #: ARP45752_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Superoxide Dismutase 1, Soluble (SOD1) peptide
SOD1 Reactivity: Human, Mouse, Rat, Dog Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
- Background
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SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Alias Symbols: ALS, ALS1, IPOA, SOD, homodimer, hSod1
Protein Interaction Partner: ESR1,POLR2A,CCS,BCL2,CCS,DNAJB1,HOXB2,KARS,PPP3CA,RNF19A,SOD1,BCL2,CCS,HECW1,RNF19A,SSR4,UBC
Protein Size: 154 - Molecular Weight
- 16 kDa
- Gene ID
- 6647
- NCBI Accession
- NM_000454, NP_000445
- UniProt
- P00441
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