Sirtuin 3 (SIRT3) Peptide
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- Target See all SIRT3 products
- SIRT3 (Sirtuin 3 (SIRT3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SIRT3 antibody (Catalog #: ARP32388_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SIRT3 (Sirtuin 3 (SIRT3))
- Synonyms
- zgc:158774 Peptide, sirtuin Peptide, SIR2L3 Peptide, 2310003L23Rik Peptide, AI848213 Peptide, Sir2l3 Peptide, sirtuin 3 Peptide, sirt3 Peptide, SIRT3 Peptide, Sirt3 Peptide
- Background
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SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family.
Alias Symbols: SIR2L3
Protein Interaction Partner: DNM1L,PEX5,PEX5
Protein Size: 399 - Molecular Weight
- 44 kDa
- Gene ID
- 23410
- NCBI Accession
- NM_012239, NP_036371
- UniProt
- Q9NTG7
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