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Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40) Peptide

RNF40 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN983096
  • Target See all RNF40 products
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RNF40 antibody (Catalog #: ARP43165_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    Synonyms
    AI848422 Peptide, mKIAA0661 Peptide, BRE1B Peptide, RBP95 Peptide, STARING Peptide, ring finger protein 40 Peptide, RNF40 Peptide, Rnf40 Peptide
    Background
    RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.

    Alias Symbols: BRE1B, DKFZp686K191, KIAA0661, MGC13051, RBP95, STARING

    Protein Interaction Partner: NCBP1,RB1,SPRYD5,UBE2L6,ZNF451,NCBP1,SPRYD5,STX1A,UBE2L6,USP15,ZNF451

    Protein Size: 1001
    Molecular Weight
    114 kDa
    Gene ID
    9810
    NCBI Accession
    NM_014771, NP_055586
    UniProt
    O75150
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