Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (Middle Region) Peptide
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- Target See all RFFL products
- RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KDQKGLQHLV SGAEDQNGGA VPSGLEENLC KICMDSPIDC VLLECGHMVT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RFFL Antibody(ARP42986_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))
- Synonyms
- MGC84042 Peptide, RFFL Peptide, Rffl Peptide, 1700051E09Rik Peptide, 4930516L10Rik Peptide, BG080975 Peptide, Carp2 Peptide, CARP-2 Peptide, CARP2 Peptide, FRING Peptide, RIFIFYLIN Peptide, RNF189 Peptide, RNF34L Peptide, ring finger and FYVE like domain containing E3 ubiquitin protein ligase Peptide, ring finger and FYVE-like domain containing E3 ubiquitin protein ligase L homeolog Peptide, ring finger and FYVE-like domain containing 1 Peptide, ring finger and FYVE like domain containing protein Peptide, ring finger and FYVE-like domain containing E3 ubiquitin protein ligase Peptide, RFFL Peptide, rffl.L Peptide, Rffl Peptide
- Background
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RFFL has E3 ubiquitin protein ligase activity.RFFL regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity.RFFL may bind phosphatidylinositol phosphates.
Alias Symbols: RNF189, RNF34L, CARP2, FRING, CARP-2, RIFIFYLIN
Protein Interaction Partner: UBE2G2
Protein Size: 363 - Molecular Weight
- 40 kDa
- Gene ID
- 117584
- NCBI Accession
- NM_001017368, NP_001017368
- UniProt
- Q8WZ73
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