Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) (Middle Region) Peptide
RECK
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all RECK products
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
- Protein Region
- Middle Region
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SCIVGGKRKS HGTSFTIDCN VCSCFAGNLV CSTRLCLSEH SSDDDRRTFT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Reck Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
- Background
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Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Alias Symbols: MGC169689, St15, mRECK
Protein Size: 971 - Molecular Weight
- 104 kDa
- Gene ID
- 53614
- NCBI Accession
- NM_016678, NP_057887
- UniProt
- Q9Z0J1
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