Retinoblastoma 1 (RB1) (Middle Region) Peptide
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- Target See all Retinoblastoma 1 (RB1) products
- Retinoblastoma 1 (RB1)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RB1 antibody (Catalog #: ARP58066_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Retinoblastoma 1 (RB1)
- Synonyms
- OSRC Peptide, RB Peptide, p105-Rb Peptide, pRb Peptide, pp110 Peptide, Rb Peptide, Rb-1 Peptide, P105-RB Peptide, PP110 Peptide, RB11 Peptide, zgc:154147 Peptide, RB transcriptional corepressor 1 Peptide, RB transcriptional corepressor like 1 Peptide, retinoblastoma 1 Peptide, RB1 Peptide, RBL1 Peptide, Rb1 Peptide, rb1 Peptide
- Background
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The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophospho
Alias Symbols: OSRC, RB, pRb, pp110, p105-Rb
Protein Interaction Partner: AATF,ABL1,AR,ATF2,BDP1,BGLAP,BIRC5,BNC2,BRCA1,BRD2,BRD8,CASP10,CASP2,CASP3,CASP6,CASP7,CASP8,CASP9,CCND1,CDK2,CDK4,CDK6,CDK6,CDKN1A,CEBPD,CEBPE,DNMT1,E1A,E2F1,E2F1,E2F1,E2F1,E2F1,E2F1,E2F2,E2F2,E2F2,EID1,EID1,EPO,FRK,GNB2L1,GTF3C2,HDAC1,HDAC1,HIF1A,HMGB1,JUN,KAT2B,KDM5A,KDM5A,LIN37,LIN54,LIN9,LMNA,MAPK1,MAPK9,MCM7,MDM2,MDM2,MDM4,MITF,MT1G,NCOA6,PELP1,PIK3R1,PIK3R3,PPIA,RAF1,RBBP4,RBBP7,RBL1,RUNX2,SERPINB2,SKP2,SNAPC1,SNAPC3,SV40gp6,TAF1,TBP,TMPO,TYR,UBE2I,UL122,VEGFA,ZBTB16,AATF,ABL1,AHR,AR,ARID3B,ATF2,BAG1,BDP1,BNC2,BRCA1,BRF1,CASP10,CASP2,CASP3,CASP6,CASP7,CASP8,CASP9,CBX4,CCNA1,CCND1,CCND2,CCNT2,CDC27,CDK1,CDK14,CDK2,CDK4,CDK6,CDK9,CDKN1A,CEBPA,CEBPB,CEBPD,CEBPE,CREG1,CTBP1,CUX1,DGKZ,DNMT1,E2F1,E2F2,E2F3,E2F4,E4F1,EID1,ELF1,ENC1,EP300,FOS,FRK,GNB2L1,GTF3C2,HBP1,HDAC1,HDAC3,HMGB1,HSPA8,ID2,INS,JUN,KDM5A,KDM5B,L3MBTL,LIN9,LMNA,MAPK1,MAPK9,MCM7,MDM2,MDM4,MNAT1,MNDA,MORF4L1,MORF4L2,MYC,MYOD1,NCOA6,NDC80,PA2G4,PAX2,PAX5,PELP1,PHB,PIK3R1,PIK3R3,PML,POLA1,PPIA,PPP1CA,PPP1CB,PPP1CC,PRDM2,PRKCB,PRKRA,PRMT2,PSMD10,PURA,RAF1,RB1,RBAK,RBBP4,RBBP5,RBBP7,RBBP8,RBBP9,RING1,RNF40,RUNX2,SERPINB2,SKP2,SMARCA4,SMARCB1,SNAPC1,SNAPC3,SNW1,SP1,SP3,SPI1,SPIB,SUV39H1,SUV420H2,TAF1,TBP,TFAP2A,TGM2,THOC1,TMPO,TOP2A,TRAP1,TRIM27,TRIP11,UBTF,USP4,ZBTB16,AATF,ABL1,AHR,AR,ARID3B,ARID4A,ARNT,ATF2,BAG1,BCR,BRCA1,BRF1,CBX1,CBX4,CBX5,CCNA1,CCND1,CCND3,CCNT2,CDK2,CDK9,CEBPB,CREG1,CUX1,DNMT1,DNMT3A,E2F1,E2F2,E2F4,E4F1,EID1,ENC1,FIE,FRK,GNB2L1,HBP1,HDAC1,HDAC2,HDAC3,HMGB1,JUN,KDM5A,L3MBTL,L3MBTL2,LIN9,LMNA,MCM7,MDM2,MNAT1,MORF4L1,MORF4L2,MRFAP1,MYC,MYOD1,NCOA6,NFIX,PA2G4,PAX6,PELP1,PHB,PIK3R3,PML,POLA1,PPARG,PRDM2,PRKRA,RAF1,RBBP4,RBBP5,RBBP7,RBBP8,RBBP9,RBL1,RBL2,RFC1,RING1,SERPINB2,SMARCA4,SNAPC1,SNAPC3,SNW1,SP1,SUV39H1,Smarca4,TAF1,TBP,TFDP1,TFDP2,TGM2,THOC1,TMPO,TP73,TRAP1,TRIP11,UBTF,USP4,VDR
Protein Size: 928 - Molecular Weight
- 106 kDa
- Gene ID
- 5925
- NCBI Accession
- NM_000321, NP_000312
- UniProt
- P06400
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