Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2) (C-Term) Peptide
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- Target See all RAC2 products
- RAC2 (Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2))
- Protein Region
- C-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LALAKDIDSV KYLECSALTQ RGLKTVFDEA IRAVLCPQPT RQQKRPCSLL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Rac2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RAC2 (Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2))
- Synonyms
- rac2 Peptide, AI323801 Peptide, AI452260 Peptide, EN-7 Peptide, Gx Peptide, HSPC022 Peptide, p21-Rac2 Peptide, ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) Peptide, RAS-related C3 botulinum substrate 2 Peptide, Rac family small GTPase 2 Peptide, rac2 Peptide, Rac2 Peptide, RAC2 Peptide
- Background
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Rac2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state it binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Rac2 augments the production of reactive oxygen species (ROS) by NADPH oxidase.
Alias Symbols: AI323801, AI452260
Protein Interaction Partner: Pak1,SMAD4
Protein Size: 192 - Molecular Weight
- 21 kDa
- Gene ID
- 19354
- NCBI Accession
- NM_009008, NP_033034
- UniProt
- Q05144
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