Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide
PYHIN1
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all PYHIN1 products
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PYHIN1 antibody (Catalog #: ARP50876_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- Synonyms
- IFIX Peptide, RP11-520H16.1 Peptide, 4930422C14 Peptide, AI447904 Peptide, Ifi209 Peptide, Ifix Peptide, pyrin and HIN domain family member 1 Peptide, interferon activated gene 209 Peptide, PYHIN1 Peptide, Ifi209 Peptide
- Background
-
PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Size: 452 - Molecular Weight
- 51 kDa
- Gene ID
- 149628
- NCBI Accession
- NM_198930, NP_945148
-
You are here:
