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Proteinase 3 (PRTN3) (N-Term) Peptide

PRTN3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982314
  • Target See all PRTN3 products
    PRTN3 (Proteinase 3 (PRTN3))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    IPQRLVNVVL GAHNVRTQEP TQQHFSVAQV FLNNYDAENK LNDVLLIQLS
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PRTN3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PRTN3 (Proteinase 3 (PRTN3))
    Background
    PRTN3 is a polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.

    Alias Symbols: ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP4, P29, PR-3, PR3

    Protein Interaction Partner: CAMP,ELN,F2R,F2RL1,IL1B,IL32,ITGB2,RELA,SERPINA1,SERPINB1,SERPINB13,SMAD3,TNF,ELN,ITGAM,SERPINA1,SERPINB1

    Protein Size: 256
    Molecular Weight
    28 kDa
    Gene ID
    5657
    NCBI Accession
    NM_002777, NP_002768
    UniProt
    P24158
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