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Pirin (PIR) Peptide

PIR Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981785
  • Target See all Pirin (PIR) products
    Pirin (PIR)
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PIR antibody (Catalog #: ARP33665_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Pirin (PIR)
    Synonyms
    ATPIRIN1 Peptide, PRN1 Peptide, pirin Peptide, 2310042L19Rik Peptide, Pirnl Peptide, zgc:92778 Peptide, xpir Peptide, pirin Peptide, pirin L homeolog Peptide, PIR Peptide, PRN Peptide, Pir Peptide, pir Peptide, pir.L Peptide
    Background
    PIR is a member of the cupin superfamily. The protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.

    Protein Interaction Partner: NFIX,SMAD9,BCL3,NFIX,NFKBIA

    Protein Size: 290
    Molecular Weight
    32 kDa
    Gene ID
    8544
    NCBI Accession
    NM_003662, NP_003653
    UniProt
    O00625
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