Pirin (PIR) Peptide
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- Target See all Pirin (PIR) products
- Pirin (PIR)
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PIR antibody (Catalog #: ARP33664_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Pirin (PIR)
- Synonyms
- ATPIRIN1 Peptide, PRN1 Peptide, pirin Peptide, 2310042L19Rik Peptide, Pirnl Peptide, zgc:92778 Peptide, xpir Peptide, pirin Peptide, pirin L homeolog Peptide, PIR Peptide, PRN Peptide, Pir Peptide, pir Peptide, pir.L Peptide
- Background
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PIR is a member of the cupin superfamily. The protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
Protein Interaction Partner: NFIX,SMAD9,BCL3,NFIX,NFKBIA
Protein Size: 290 - Molecular Weight
- 32 kDa
- Gene ID
- 8544
- NCBI Accession
- NM_003662, NP_003653
- UniProt
- O00625
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